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Extracellular vesicles and nanoparticles: emerging complexities

Dennis K. Jeppesen, Qin Zhang, Jeffrey L. Franklin, Robert J. Coffey

Trends in Cell Biology · 2023 · ▲ 631 citations

Altered intercellular communication Review

Abstract

The study of extracellular vesicles (EVs) and nanoparticles (NPs) is rapidly expanding because recent discoveries have revealed a much greater complexity and diversity than was appreciated only a few years ago. New types of EVs and NPs have recently been described. Proteins and nucleic acids previously thought to be packaged in exosomes appear to be more enriched in different types of EVs and in two recently identified amembranous NPs, exomeres and supermeres. Thus, our understanding of the cell biology and intercellular communication facilitated by the release of EVs and NPs is in a state of flux. In this review, we describe the different types of EVs and NPs, highlight recent advances, and present major outstanding questions.

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Provenance

Source: OpenAlex
DOI: 10.1016/j.tcb.2023.01.002
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Fetched: 2026-06-13 MST

Cite this

APA

Jeppesen, D.K., Zhang, Q., Franklin, J.L., & Coffey, R.J. (2023). Extracellular vesicles and nanoparticles: emerging complexities. <em>Trends in Cell Biology</em>. https://doi.org/10.1016/j.tcb.2023.01.002

Vancouver

Jeppesen DK, Zhang Q, Franklin JL, Coffey RJ. Extracellular vesicles and nanoparticles: emerging complexities. Trends in Cell Biology. 2023. doi:10.1016/j.tcb.2023.01.002.

BibTeX

@article{dennis2023Extrac, title = {Extracellular vesicles and nanoparticles: emerging complexities}, author = {Dennis K. Jeppesen and Qin Zhang and Jeffrey L. Franklin and Robert J. Coffey}, journal = {Trends in Cell Biology}, year = {2023}, doi = {10.1016/j.tcb.2023.01.002}, }