Open access · OA via Europe PMC

Experimental Evidence Against Taurine Deficiency as a Driver of Aging in Humans.

Marcangeli V, Cefis M, Hammad R, Granet J, Leduc-Gaudet JP, Gaudreau P, Aubertin-Leheudre M, Bélanger M, Robitaille R, Morais JA, Gouspillou G.

Aging cell · 2025 · ▲ 3 citations

Mitochondrial dysfunction Human

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Abstract

Taurine deficiency was recently proposed as a driver of aging in various species, including humans. To test this hypothesis, we assessed whether circulating taurine was associated with aging and physical performance in 137 physically inactive and physically active men aged 20-93. No association between circulating taurine levels and age, muscle mass, strength, physical performance, or mitochondrial function was observed, thereby challenging the implication of taurine deficiency as a primary driver of aging in humans.

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Provenance

Source: Europe PMC
DOI: 10.1111/acel.70191
Canonical: link ↗
Fetched: 2026-07-01 MST

Cite this

APA

V, M., M, C., R, H., J, G., JP, L., P, G., M, A., M, B., R, R., JA, M., & G., G. (2025). Experimental Evidence Against Taurine Deficiency as a Driver of Aging in Humans. <em>Aging cell</em>. https://doi.org/10.1111/acel.70191

Vancouver

V M, M C, R H, J G, JP L, P G, et al. Experimental Evidence Against Taurine Deficiency as a Driver of Aging in Humans. Aging cell. 2025. doi:10.1111/acel.70191.

BibTeX

@article{marcangeli2025Experi, title = {Experimental Evidence Against Taurine Deficiency as a Driver of Aging in Humans.}, author = {Marcangeli V and Cefis M and Hammad R and Granet J and Leduc-Gaudet JP and Gaudreau P and Aubertin-Leheudre M and Bélanger M and Robitaille R and Morais JA and Gouspillou G.}, journal = {Aging cell}, year = {2025}, doi = {10.1111/acel.70191}, }