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Experimental Evidence Against Taurine Deficiency as a Driver of Aging in Humans

Vincent Marcangeli, Marina Cefis, Rami Hammad, Jordan Granet, Jean‐Philippe Leduc‐Gaudet, Pierrette Gaudreau, Mylène Aubertin‐Leheudre, Marc Bélanger, Richard Robitaille, José A. Morais, Gilles Gouspillou

Aging Cell · 2025 · ▲ 5 citations

Abstract

Taurine deficiency was recently proposed as a driver of aging in various species, including humans. To test this hypothesis, we assessed whether circulating taurine was associated with aging and physical performance in 137 physically inactive and physically active men aged 20-93. No association between circulating taurine levels and age, muscle mass, strength, physical performance, or mitochondrial function was observed, thereby challenging the implication of taurine deficiency as a primary driver of aging in humans.

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Provenance

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OpenAlex
DOI
10.1111/acel.70191
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2026-06-23 MST

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APA
Marcangeli, V., Cefis, M., Hammad, R., Granet, J., Leduc‐Gaudet, J., Gaudreau, P., Aubertin‐Leheudre, M., Bélanger, M., Robitaille, R., Morais, J.A., &amp; Gouspillou, G. (2025). Experimental Evidence Against Taurine Deficiency as a Driver of Aging in Humans. <em>Aging Cell</em>. https://doi.org/10.1111/acel.70191
Vancouver
Marcangeli V, Cefis M, Hammad R, Granet J, Leduc‐Gaudet J, Gaudreau P, et al. Experimental Evidence Against Taurine Deficiency as a Driver of Aging in Humans. Aging Cell. 2025. doi:10.1111/acel.70191.
BibTeX
@article{vincent2025Experi, title = {Experimental Evidence Against Taurine Deficiency as a Driver of Aging in Humans}, author = {Vincent Marcangeli and Marina Cefis and Rami Hammad and Jordan Granet and Jean‐Philippe Leduc‐Gaudet and Pierrette Gaudreau and Mylène Aubertin‐Leheudre and Marc Bélanger and Richard Robitaille and José A. Morais and Gilles Gouspillou}, journal = {Aging Cell}, year = {2025}, doi = {10.1111/acel.70191}, }

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