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Echoes of Muscle Aging: The Emerging Role of Shear Wave Elastography in Sarcopenia Diagnosis

Linda Galasso, Federica Vitale, Manuela Pietramale, Giorgio Esposto, Raffaele Borriello, Irene Mignini, Antonio Gasbarrini, Maria Elena Ainora, Maria Assunta Zocco

Diagnostics · 2025 · ▲ 5 citations

Abstract

Sarcopenia, a progressive age-related loss of skeletal muscle mass, strength, and function, is a major contributor to disability, reduced quality of life, and mortality in older adults. While current diagnostic approaches, such as dual-energy X-ray absorptiometry (DXA), bioelectrical impedance analysis (BIA), magnetic resonance imaging (MRI), and computed tomography (CT), are widely used to assess muscle mass, they have limitations in detecting early qualitative changes in muscle architecture and composition. Shear Wave Elastography (SWE), an ultrasound-based technique that quantifies tissue stiffness, has emerged as a promising tool to evaluate both muscle quantity and quality in a non-invasive, portable, and reproducible manner. Studies suggest that SWE can detect alterations in muscle mechanical properties associated with sarcopenia, providing complementary information to traditional morphometric assessments. Preliminary evidence indicates its good reproducibility, feasibility in various clinical settings, and potential for integration into routine evaluations. This narrative review summarizes current evidence on the use of SWE for the assessment of sarcopenia across diverse populations.

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OpenAlex
DOI
10.3390/diagnostics15192495
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2026-10-17 MST

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APA
Galasso, L., Vitale, F., Pietramale, M., Esposto, G., Borriello, R., Mignini, I., Gasbarrini, A., Ainora, M.E., &amp; Zocco, M.A. (2025). Echoes of Muscle Aging: The Emerging Role of Shear Wave Elastography in Sarcopenia Diagnosis. <em>Diagnostics</em>. https://doi.org/10.3390/diagnostics15192495
Vancouver
Galasso L, Vitale F, Pietramale M, Esposto G, Borriello R, Mignini I, et al. Echoes of Muscle Aging: The Emerging Role of Shear Wave Elastography in Sarcopenia Diagnosis. Diagnostics. 2025. doi:10.3390/diagnostics15192495.
BibTeX
@article{linda2025Echoes, title = {Echoes of Muscle Aging: The Emerging Role of Shear Wave Elastography in Sarcopenia Diagnosis}, author = {Linda Galasso and Federica Vitale and Manuela Pietramale and Giorgio Esposto and Raffaele Borriello and Irene Mignini and Antonio Gasbarrini and Maria Elena Ainora and Maria Assunta Zocco}, journal = {Diagnostics}, year = {2025}, doi = {10.3390/diagnostics15192495}, }

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