Deciphering the longevity of the mole-rats

A theoretical model of a nonlinear network that outlines the general aspects of mole-rat resistance to age-related diseases, such as cancer and the action of ROS was elaborated. According to our conjecture, it was shown that the protection is established because hyaluronic acid of high molecular mass forms a non-linear network of interactions. That network leads to self-organization away from the thermodynamical equilibrium, which appears through a “first order” phase transition as a supercritical bifurcation of Andronov-Hopf type. Finally, it is shown how the rate of entropy production is a Lyapunov function of the dynamics of the process.