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Current Methods for Skeletal Muscle Tissue Repair and Regeneration

Juan Liu, Dominik Saul, Kai O. Böker, Jennifer Ernst, Wolfgang Lehman, Arndt F. Schilling

BioMed Research International · 2018 · ▲ 190 citations

Abstract

Skeletal muscle has the capacity of regeneration after injury. However, for large volumes of muscle loss, this regeneration needs interventional support. Consequently, muscle injury provides an ongoing reconstructive and regenerative challenge in clinical work. To promote muscle repair and regeneration, different strategies have been developed within the last century and especially during the last few decades, including surgical techniques, physical therapy, biomaterials, and muscular tissue engineering as well as cell therapy. Still, there is a great need to develop new methods and materials, which promote skeletal muscle repair and functional regeneration. In this review, we give a comprehensive overview over the epidemiology of muscle tissue loss, highlight current strategies in clinical treatment, and discuss novel methods for muscle regeneration and challenges for their future clinical translation.

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Provenance

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OpenAlex
DOI
10.1155/2018/1984879
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2026-06-11 MST

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APA
Liu, J., Saul, D., Böker, K.O., Ernst, J., Lehman, W., &amp; Schilling, A.F. (2018). Current Methods for Skeletal Muscle Tissue Repair and Regeneration. <em>BioMed Research International</em>. https://doi.org/10.1155/2018/1984879
Vancouver
Liu J, Saul D, Böker KO, Ernst J, Lehman W, Schilling AF. Current Methods for Skeletal Muscle Tissue Repair and Regeneration. BioMed Research International. 2018. doi:10.1155/2018/1984879.
BibTeX
@article{juan2018Curren, title = {Current Methods for Skeletal Muscle Tissue Repair and Regeneration}, author = {Juan Liu and Dominik Saul and Kai O. Böker and Jennifer Ernst and Wolfgang Lehman and Arndt F. Schilling}, journal = {BioMed Research International}, year = {2018}, doi = {10.1155/2018/1984879}, }

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