Open access · US-GOV via ClinicalTrials.gov Clinical trial

Combining Exercise Training With a Drug to Break AGE-crosslinks; Effects on Cardiovascular Structure and Function and Related Mechanisms

Authors not listed

Radboud University Medical Center · 2008

Dysbiosis Exercise Human Randomized controlled trial

Abstract

Healthy but sedentary aging leads to increased morbidity and mortality of cardiovascular disease. This is partly due to the accumulation of Advanced Glycation Endproducts (AGEs) and the stiffening of the myocardium and arteries. New medication has been developed to break these AGE-crosslinks to improve cardiovascular compliance. The positive influence of regular physical activity is well known for cardiovascular disease and aging. Therefore, what is the most effective intervention, physical exercise and/or new medication AGE-crosslink breakers, in improving the cardiovascular and cerebrovascular compliance and improving the endothelial function in healthy sedentary elderly.

◌ CITATION ONLY
Full text is not openly licensed for redistribution here. Read it at the source:

Read at source →

Provenance

Source: ClinicalTrials.gov
Canonical: link ↗
Fetched: 2026-10-24 MST

Cite this

APA

Anonymous. (2008). Combining Exercise Training With a Drug to Break AGE-crosslinks; Effects on Cardiovascular Structure and Function and Related Mechanisms. <em>Radboud University Medical Center</em>. https://clinicaltrials.gov/study/NCT01417663

Vancouver

Anonymous. Combining Exercise Training With a Drug to Break AGE-crosslinks; Effects on Cardiovascular Structure and Function and Related Mechanisms. Radboud University Medical Center. 2008.

BibTeX

@misc{anon2008Combin, title = {Combining Exercise Training With a Drug to Break AGE-crosslinks; Effects on Cardiovascular Structure and Function and Related Mechanisms}, author = {Anonymous}, journal = {Radboud University Medical Center}, year = {2008}, }