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Brief guide to senescence assays using cultured mammalian cells

Eun Seok Kang, Chanhee Kang, Young‐Sam Lee, Seung‐Jae Lee

Molecules and Cells · 2024 · ▲ 22 citations

Cellular senescence

Abstract

Cellular senescence is a crucial biological process associated with organismal aging and many chronic diseases. Here, we present a brief guide to mammalian senescence assays, including the measurement of cell cycle arrest, change in cellular morphology, senescence-associated β-galactosidase (SA-β-gal) staining, and the expression of senescence-associated secretory phenotype (SASP). This work will be useful for biologists with minimum expertise in cellular senescence assays.

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Provenance

Source: OpenAlex
DOI: 10.1016/j.mocell.2024.100102
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Fetched: 2026-06-07 MST

Cite this

APA

Kang, E.S., Kang, C., Lee, Y., & Lee, S. (2024). Brief guide to senescence assays using cultured mammalian cells. <em>Molecules and Cells</em>. https://doi.org/10.1016/j.mocell.2024.100102

Vancouver

Kang ES, Kang C, Lee Y, Lee S. Brief guide to senescence assays using cultured mammalian cells. Molecules and Cells. 2024. doi:10.1016/j.mocell.2024.100102.

BibTeX

@article{eun2024Briefg, title = {Brief guide to senescence assays using cultured mammalian cells}, author = {Eun Seok Kang and Chanhee Kang and Young‐Sam Lee and Seung‐Jae Lee}, journal = {Molecules and Cells}, year = {2024}, doi = {10.1016/j.mocell.2024.100102}, }