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ATM‐dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post‐translational activation of p53 protein involving poly(ADP‐ribose) polymerase

Homayoun Vaziri, Michael D. West, Richard Allsopp, Timothy S. Davison, Yu‐Sung Wu, C.H. Arrowsmith, Guy G. Poirier, Samuel Benchimol

The EMBO Journal · 1997 · ▲ 386 citations

Genomic instability Telomere attrition Cell culture / in vitro Human

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Abstract

This 1997 study in The EMBO Journal examines the relationship between telomere loss, DNA damage, and the activation of p53 protein in human fibroblasts.

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Provenance

Source: OpenAlex
DOI: 10.1093/emboj/16.19.6018
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Fetched: 2026-10-03 MST

Cite this

APA

Vaziri, H., West, M.D., Allsopp, R., Davison, T.S., Wu, Y., Arrowsmith, C., Poirier, G.G., & Benchimol, S. (1997). ATM‐dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post‐translational activation of p53 protein involving poly(ADP‐ribose) polymerase. <em>The EMBO Journal</em>. https://doi.org/10.1093/emboj/16.19.6018

Vancouver

Vaziri H, West MD, Allsopp R, Davison TS, Wu Y, Arrowsmith C, et al. ATM‐dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post‐translational activation of p53 protein involving poly(ADP‐ribose) polymerase. The EMBO Journal. 1997. doi:10.1093/emboj/16.19.6018.

BibTeX

@article{homayoun1997ATMdep, title = {ATM‐dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post‐translational activation of p53 protein involving poly(ADP‐ribose) polymerase}, author = {Homayoun Vaziri and Michael D. West and Richard Allsopp and Timothy S. Davison and Yu‐Sung Wu and C.H. Arrowsmith and Guy G. Poirier and Samuel Benchimol}, journal = {The EMBO Journal}, year = {1997}, doi = {10.1093/emboj/16.19.6018}, }