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An Overview: The Diversified Role of Mitochondria in Cancer Metabolism

Yue Liu, Yihong Sun, Yadong Guo, Xiaoyun Shi, Xi Chen, Wenfeng Feng, Leilei Wu, Jin Zhang, Shibo Yu, Yi Wang, Yufeng Shi

International Journal of Biological Sciences · 2023 · ▲ 227 citations

Mitochondrial dysfunction Stem-cell exhaustion Review

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Abstract

/NADH to prevent metastasis and progression of cancers. In this review, we discussed mitochondrial function in cancer cell metabolism and specially explored the unique role of mitochondria in cancer stem cells and the tumor microenvironment. Targeting the OXPHOS pathway and mitochondria-related metabolism emerging as a potential therapeutic strategy for various cancers.

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Provenance

Source: OpenAlex
DOI: 10.7150/ijbs.81609
Canonical: link ↗
Fetched: 2026-06-01 MST

Cite this

APA

Liu, Y., Sun, Y., Guo, Y., Shi, X., Chen, X., Feng, W., Wu, L., Zhang, J., Yu, S., Wang, Y., & Shi, Y. (2023). An Overview: The Diversified Role of Mitochondria in Cancer Metabolism. <em>International Journal of Biological Sciences</em>. https://doi.org/10.7150/ijbs.81609

Vancouver

Liu Y, Sun Y, Guo Y, Shi X, Chen X, Feng W, et al. An Overview: The Diversified Role of Mitochondria in Cancer Metabolism. International Journal of Biological Sciences. 2023. doi:10.7150/ijbs.81609.

BibTeX

@article{yue2023AnOver, title = {An Overview: The Diversified Role of Mitochondria in Cancer Metabolism}, author = {Yue Liu and Yihong Sun and Yadong Guo and Xiaoyun Shi and Xi Chen and Wenfeng Feng and Leilei Wu and Jin Zhang and Shibo Yu and Yi Wang and Yufeng Shi}, journal = {International Journal of Biological Sciences}, year = {2023}, doi = {10.7150/ijbs.81609}, }