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Ageing: from inflammation to cancer

Giulia C. Leonardi, Giulia Accardi, Roberto Monastero, Ferdinando Nicoletti, Massimo Libra

Immunity & Ageing · 2018 · ▲ 234 citations

Chronic inflammation Review
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Abstract

Ageing is the major risk factor for cancer development. Hallmark of the ageing process is represented by inflammaging(definition), which is a chronic and systemic low-grade inflammatory process. Inflammation is also a hallmark of cancer and is widely recognized to influence all cancer stages from cell transformation to metastasis. Therefore, inflammaging may represent the biological phenomena able to couple ageing process with cancer development. Here we review the molecular and cellular pathway involved in age-related chronic inflammation along with its potential triggers and their connection with cancer development.

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Provenance

Source
OpenAlex
DOI
10.1186/s12979-017-0112-5
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Fetched
2026-06-08 MST

Cite this

APA
Leonardi, G.C., Accardi, G., Monastero, R., Nicoletti, F., &amp; Libra, M. (2018). Ageing: from inflammation to cancer. <em>Immunity & Ageing</em>. https://doi.org/10.1186/s12979-017-0112-5
Vancouver
Leonardi GC, Accardi G, Monastero R, Nicoletti F, Libra M. Ageing: from inflammation to cancer. Immunity & Ageing. 2018. doi:10.1186/s12979-017-0112-5.
BibTeX
@article{giulia2018Ageing, title = {Ageing: from inflammation to cancer}, author = {Giulia C. Leonardi and Giulia Accardi and Roberto Monastero and Ferdinando Nicoletti and Massimo Libra}, journal = {Immunity & Ageing}, year = {2018}, doi = {10.1186/s12979-017-0112-5}, }

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