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Adipose tissue macrophages in aging-associated adipose tissue function

Bangchao Lu, Liang Huang, Juan Cao, Lingling Li, Wenhui Wu, Xiaolin Chen, Congzhu Ding

The Journal of Physiological Sciences · 2021 · ▲ 33 citations

Chronic inflammation Review

Abstract

"Inflammaging" refers to the chronic, low-grade inflammation that characterizes aging. Aging, like obesity, is associated with visceral adiposity and insulin resistance. Adipose tissue macrophages (ATMs) have played a major role in obesity-associated inflammation and insulin resistance. Macrophages are elevated in adipose tissue in aging. However, the changes and also possibly functions of ATMs in aging and aging-related diseases are unclear. In this review, we will summarize recent advances in research on the role of adipose tissue macrophages with aging-associated insulin resistance and discuss their potential therapeutic targets for preventing and treating aging and aging-related diseases.

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Provenance

Source: OpenAlex
DOI: 10.1186/s12576-021-00820-2
Canonical: link ↗
Fetched: 2026-06-08 MST

Cite this

APA

Lu, B., Huang, L., Cao, J., Li, L., Wu, W., Chen, X., & Ding, C. (2021). Adipose tissue macrophages in aging-associated adipose tissue function. <em>The Journal of Physiological Sciences</em>. https://doi.org/10.1186/s12576-021-00820-2

Vancouver

Lu B, Huang L, Cao J, Li L, Wu W, Chen X, et al. Adipose tissue macrophages in aging-associated adipose tissue function. The Journal of Physiological Sciences. 2021. doi:10.1186/s12576-021-00820-2.

BibTeX

@article{bangchao2021Adipos, title = {Adipose tissue macrophages in aging-associated adipose tissue function}, author = {Bangchao Lu and Liang Huang and Juan Cao and Lingling Li and Wenhui Wu and Xiaolin Chen and Congzhu Ding}, journal = {The Journal of Physiological Sciences}, year = {2021}, doi = {10.1186/s12576-021-00820-2}, }