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Accelerated Biological Aging is Associated With Increased Risk of T2DM in the MASLD Population: a Cohort Study

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Ningbo No. 1 Hospital · 2025

Abstract

The association between biological aging and type 2 diabetes mellitus (T2DM) incidence in individuals with and without metabolic dysfunction-associated steatotic liver disease (MASLD) remains unclear.We assessed biological age by calculating phenotypic age (PhenoAge), Klemera-Doubal method (KDMAge), and homeostatic dysregulation (HDAge). To examine the association of biological ageing with the risk of T2DM, cox regression models were conducted. Furthermore, we applied survival analysis, restricted cubic spline models and population attributable fraction (PAF) to further evaluate the association between biological ageing and T2DM incidence.

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ClinicalTrials.gov
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2026-10-14 MST

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APA
Anonymous. (2025). Accelerated Biological Aging is Associated With Increased Risk of T2DM in the MASLD Population: a Cohort Study. <em>Ningbo No. 1 Hospital</em>. https://clinicaltrials.gov/study/NCT06984510
Vancouver
Anonymous. Accelerated Biological Aging is Associated With Increased Risk of T2DM in the MASLD Population: a Cohort Study. Ningbo No. 1 Hospital. 2025.
BibTeX
@misc{anon2025Accele, title = {Accelerated Biological Aging is Associated With Increased Risk of T2DM in the MASLD Population: a Cohort Study}, author = {Anonymous}, journal = {Ningbo No. 1 Hospital}, year = {2025}, }

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