Open access · US-GOV via ClinicalTrials.gov Clinical trial

A Dose-ranging, Randomized, Double-blind , Placebo-controlled Study of the Effect of RO5313534, Used as add-on Therapy to Donepezil, on Cognitive Function in Patients With Mild to Moderate Symptoms of Alzheimer's Disease

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Hoffmann-La Roche · 2009

Dysbiosis Human Randomized controlled trial

Abstract

This 4 arm study will assess the efficacy and safety of RO5313534 (MEM3454) versus placebo added to donepezil, in patients with mild to moderate Alzheimer's disease. Following a screening period, patients will be randomized to one of 4 treatments (placebo, or RO5313534 1mg, 5mg or 15mg po daily) with background therapy of donepezil (5mg or 10mg).The anticipated time on study treatment is 6 months, and the target sample size is 100-500 individuals.

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Source: ClinicalTrials.gov
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Fetched: 2026-10-19 MST

Cite this

APA

Anonymous. (2009). A Dose-ranging, Randomized, Double-blind , Placebo-controlled Study of the Effect of RO5313534, Used as add-on Therapy to Donepezil, on Cognitive Function in Patients With Mild to Moderate Symptoms of Alzheimer's Disease. <em>Hoffmann-La Roche</em>. https://clinicaltrials.gov/study/NCT00884507

Vancouver

Anonymous. A Dose-ranging, Randomized, Double-blind , Placebo-controlled Study of the Effect of RO5313534, Used as add-on Therapy to Donepezil, on Cognitive Function in Patients With Mild to Moderate Symptoms of Alzheimer's Disease. Hoffmann-La Roche. 2009.

BibTeX

@misc{anon2009ADoser, title = {A Dose-ranging, Randomized, Double-blind , Placebo-controlled Study of the Effect of RO5313534, Used as add-on Therapy to Donepezil, on Cognitive Function in Patients With Mild to Moderate Symptoms of Alzheimer's Disease}, author = {Anonymous}, journal = {Hoffmann-La Roche}, year = {2009}, }