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Evidence brief · hallmark

Telomere attrition

Synthesized from 10 indexed sources · 2026-07-27 MST · preview (no AI key)
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Across the retrieved literature, senescent-cell burden and chronic inflammation recur as central, interacting drivers, with intervention studies reporting functional gains in model organisms. Key works: [1][2][3][4][5].

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Sources

  1. [1] The Hallmarks of Aging
  2. [2] Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version (K-SADS-PL): Initial Reliability and Validity Data
  3. [3] A map of human genome variation from population-scale sequencing
  4. [4] 2021 ESC Guidelines on cardiovascular disease prevention in clinical practice
  5. [5] Hallmarks of aging: An expanding universe
  6. [6] Extension of Life-Span by Introduction of Telomerase into Normal Human Cells
  7. [7] Successful Aging
  8. [8] Successful Aging
  9. [9] Prognostic Value of CALLY Index, Frailty and SOFA-2 Score for Mortality in Geriatric Intensive Care Patients: A Prospective Cohort Study
  10. [10] Telomere Dysfunction and Extracellular Matrix Remodeling
All Telomere attrition works →