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Evidence brief · hallmark

Chronic inflammation

Synthesized from 10 indexed sources · 2026-07-27 MST · preview (no AI key)
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Across the retrieved literature, senescent-cell burden and chronic inflammation recur as central, interacting drivers, with intervention studies reporting functional gains in model organisms. Key works: [1][2][3][4][5].

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Sources

  1. [1] The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
  2. [2] 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure
  3. [3] The Occurrence of Sleep-Disordered Breathing among Middle-Aged Adults
  4. [4] Hepatocellular carcinoma
  5. [5] 2016 ESC Guidelines for the Diagnosis and Treatment of Acute and Chronic Heart Failure
  6. [6] Multi-ethnic reference values for spirometry for the 3–95-yr age range: the global lung function 2012 equations
  7. [7] Inflamm‐aging: An Evolutionary Perspective on Immunosenescence
  8. [8] The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression
  9. [9] Editorial: The role of immunity and inflammation in aging and aging-related diseases
  10. [10] 415 Designing nanoparticle therapies for age-related macular degeneration