Author
Yuji Ikeno
- Indexed works
- 22
- Total citations
- 10,220
- Active years
- 15
Collaborators
Works in the record
Aging Cell 2015
Open access · CC-BY
The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs
Nature Medicine 2018
Preprint · OA
Senolytics improve physical function and increase lifespan in old age
Nature Cell Biology 2015
Preprint · OA
MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation
Nature Communications 2022
Open access · CC-BY
A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues
Cell Metabolism 2015
Open access · OA
A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan
Cell Metabolism 2019
Open access · CC-BY
Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis
Cell 2015
Open access · OA
Reduced Expression of MYC Increases Longevity and Enhances Healthspan
The Journals of Gerontology Series A 2013
Open access · OA
Rapamycin Extends Life and Health in C57BL/6 Mice
Redox Biology 2016
Open access · CC-BY
A new role for oxidative stress in aging: The accelerated aging phenotype in Sod1− mice is correlated to increased cellular senescence
Nature Communications 2018
Open access · CC-BY
Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice
PLoS ONE 2011
Open access · CC-BY
Does Reduced IGF-1R Signaling in Igf1r+/− Mice Alter Aging?
GeroScience 2017
Open access · OA
IGF-1 has sexually dimorphic, pleiotropic, and time-dependent effects on healthspan, pathology, and lifespan
Aging Cell 2009
Open access · OA
Lifespan extension in genetically modified mice
PLoS ONE 2010
Open access · CC-BY
Long-Term IGF-I Exposure Decreases Autophagy and Cell Viability
Aging Cell 2013
Open access · CC-BY
Reductions in serum IGF ‐1 during aging impair health span
bioRxiv (Cold Spring Harbor Laboratory) 2021
Preprint · OA
A New Gene Set Identifies Senescent Cells and Predicts Senescence-Associated Pathways Across Tissues
Cell Metabolism 2024
Preprint · OA
Intermittent clearance of p21-highly-expressing cells extends lifespan and confers sustained benefits to health and physical function
Journal of Bone and Mineral Research 2015
Open access · OA
IGF-1 Regulates Vertebral Bone Aging Through Sex-Specific and Time-Dependent Mechanisms
PubMed 1999
Preprint
Modulation of renal xanthine oxidoreductase in aging: gene expression and reactive oxygen species generation.
Annals of the New York Academy of Sciences 2015
Open access · CC-BY
Significant life extension by ten percent dietary restriction
Longevity & Healthspan 2012
Open access · CC-BY
Thioredoxin, oxidative stress, cancer and aging
bioRxiv (Cold Spring Harbor Laboratory) 2025
Preprint · OA