Author
Yi Zhu
- Indexed works
- 27
- Total citations
- 14,984
- Active years
- 13
Collaborators
Works in the record
Aging Cell 2015
Open access · CC-BY
The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs
Journal of Clinical Investigation 2013
Open access · OA
Cellular senescence and the senescent secretory phenotype: therapeutic opportunities
Nature Communications 2017
Open access · CC-BY
Cellular senescence mediates fibrotic pulmonary disease
Aging Cell 2015
Open access · CC-BY
Identification of a novel senolytic agent, navitoclax, targeting the Bcl‐2 family of anti‐apoptotic factors
EBioMedicine 2018
Open access · CC-BY
Fisetin is a senotherapeutic that extends health and lifespan
Nature 2021
Preprint · OA
An aged immune system drives senescence and ageing of solid organs
Aging 2017
Open access · CC-BY
New agents that target senescent cells: the flavone, fisetin, and the BCL-XL inhibitors, A1331852 and A1155463
Aging Cell 2016
Open access · CC-BY
Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice
Nature Communications 2017
Open access · CC-BY
Identification of HSP90 inhibitors as a novel class of senolytics
Aging Cell 2019
Open access · CC-BY
Targeting senescent cells alleviates obesity‐induced metabolic dysfunction
Journal of Clinical Investigation 2022
Open access · CC-BY
Cellular senescence: a key therapeutic target in aging and diseases
Cell Metabolism 2019
Open access · CC-BY
Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis
Aging Cell 2021
Open access · CC-BY
Whole‐body senescent cell clearance alleviates age‐related brain inflammation and cognitive impairment in mice
JCI Insight 2020
Open access · CC-BY
The senescence-associated secretome as an indicator of age and medical risk
Current Opinion in Clinical Nutrition & Metabolic Care 2014
Citation only
Cellular senescence and the senescent secretory phenotype in age-related chronic diseases
FEBS Journal 2020
Open access · CC-BY
Discovery, development, and future application of senolytics: theories and predictions
The Journals of Gerontology Series A 2016
Open access · CC-BY
17α-Estradiol Alleviates Age-related Metabolic and Inflammatory Dysfunction in Male Mice Without Inducing Feminization
Nature Communications 2017
Open access · CC-BY
Spermine synthase deficiency causes lysosomal dysfunction and oxidative stress in models of Snyder-Robinson syndrome
EBioMedicine 2022
Open access · CC-BY
Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans
Aging 2021
Open access · CC-BY
SARS-CoV-2 causes senescence in human cells and exacerbates the senescence-associated secretory phenotype through TLR-3
Journal of the American Geriatrics Society 2021
Open access · CC-BY
Fisetin for COVID ‐19 in skilled nursing facilities: Senolytic trials in the COVID era
Aging Cell 2020
Open access · CC-BY
Immune checkpoint protein VSIG4 as a biomarker of aging in murine adipose tissue
Cold Spring Harbor Perspectives in Medicine 2023
Preprint · OA
Past and Future Directions for Research on Cellular Senescence
Cell Metabolism 2025
Preprint · OA
Endothelial senescent-cell-specific clearance alleviates metabolic dysfunction in obese mice
EBioMedicine 2026
Open access · CC-BY
Senolytics, dasatanib plus quercetin, reduce kidney inflammation, senescent cell abundance, and injury while restoring geroprotective factors in murine diabetic kidney disease
EBioMedicine 2021
Open access · CC-BY
Development of a novel senolytic by precise disruption of FOXO4-p53 complex
Aging Cell 2025
Open access · CC-BY