Author
Sundeep Khosla
- Indexed works
- 30
- Total citations
- 10,257
- Active years
- 11
Collaborators
Works in the record
Aging Cell 2015
Open access · CC-BY
The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs
EBioMedicine 2019
Open access · CC-BY
Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease
Nature Medicine 2017
Preprint · OA
Targeting cellular senescence prevents age-related bone loss in mice
Aging Cell 2010
Open access · OA
Fat tissue, aging, and cellular senescence
Nature Communications 2022
Open access · CC-BY
A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues
Journal of Bone and Mineral Research 2016
Preprint · OA
Identification of Senescent Cells in the Bone Microenvironment
Nature Reviews Endocrinology 2020
Preprint · OA
The role of cellular senescence in ageing and endocrine disease
The Annual Review of Pharmacology and Toxicology 2020
Open access · OA
Senolytic Drugs: Reducing Senescent Cell Viability to Extend Health Span
Cell 2024
Open access · CC-BY
Guidelines for minimal information on cellular senescence experimentation in vivo
Bone 2019
Preprint · OA
Cellular senescence in bone
Trends in Molecular Medicine 2020
Preprint · OA
Reducing Senescent Cell Burden in Aging and Disease
Journal of Bone and Mineral Research 2020
Open access · OA
Targeted Reduction of Senescent Cell Burden Alleviates Focal Radiotherapy-Related Bone Loss
Journal of Bone and Mineral Research 2019
Open access · OA
Independent Roles of Estrogen Deficiency and Cellular Senescence in the Pathogenesis of Osteoporosis: Evidence in Young Adult Mice and Older Humans
Nature Medicine 2024
Preprint · OA
Effects of intermittent senolytic therapy on bone metabolism in postmenopausal women: a phase 2 randomized controlled trial
EBioMedicine 2022
Open access · OA
Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans
Journal of Clinical Investigation 2022
Open access · CC-BY
Cellular senescence and the skeleton: pathophysiology and therapeutic implications
Journal of Periodontology 2020
Preprint · OA
Senescent cells exacerbate chronic inflammation and contribute to periodontal disease progression in old mice
eLife 2021
Open access · CC-BY
Modulation of fracture healing by the transient accumulation of senescent cells
EBioMedicine 2020
Open access · CC-BY
Corrigendum to ‘Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease’ EBioMedicine 47 (2019) 446–456
bioRxiv (Cold Spring Harbor Laboratory) 2021
Preprint · OA
A New Gene Set Identifies Senescent Cells and Predicts Senescence-Associated Pathways Across Tissues
Nature Communications 2023
Open access · CC-BY
Multiparametric senescent cell phenotyping reveals targets of senolytic therapy in the aged murine skeleton
Current Osteoporosis Reports 2020
Preprint · OA
Osteocyte Cellular Senescence
Journal of the American Geriatrics Society 2021
Open access · CC-BY
Fisetin for <scp>COVID</scp> ‐19 in skilled nursing facilities: Senolytic trials in the <scp>COVID</scp> era
Journal of Bone and Mineral Research 2020
Preprint · OA
Bone Marrow Adiposity in Models of Radiation- and Aging-Related Bone Loss Is Dependent on Cellular Senescence
Nature Aging 2023
Preprint · OA
Senescent cells, senolytics and tissue repair: the devil may be in the dosing
The Journals of Gerontology Series A 2023
Open access · CC0
Drugs Targeting Mechanisms of Aging to Delay Age-Related Disease and Promote Healthspan: Proceedings of a National Institute on Aging Workshop
bioRxiv (Cold Spring Harbor Laboratory) 2023
Preprint · CC-BY
Distinct secretomes in p16- and p21- positive senescent cells across tissues
Aging Cell 2025
Open access · CC-BY
Characterization of Human Senescent Cell Biomarkers for Clinical Trials
Cell Metabolism 2025
Preprint · OA
Endothelial senescent-cell-specific clearance alleviates metabolic dysfunction in obese mice
bioRxiv (Cold Spring Harbor Laboratory) 2021
Preprint · CC-BY