Author
Sundeep Khosla
- Indexed works
- 44
- Total citations
- 13,146
- Active years
- 17
Collaborators
Works in the record
Aging Cell 2015
Open access · CC-BY
The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs
EBioMedicine 2019
Open access · CC-BY
Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease
Journal of Bone and Mineral Research 1998
Citation only
A Unitary Model for Involutional Osteoporosis: Estrogen Deficiency Causes Both Type I and Type II Osteoporosis in Postmenopausal Women and Contributes to Bone Loss in Aging Men
Aging Cell 2010
Open access · OA
Fat tissue, aging, and cellular senescence
Nature Medicine 2017
Preprint · OA
Targeting cellular senescence prevents age-related bone loss in mice
Nature Communications 2022
Open access · CC-BY
A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues
Journal of the American Geriatrics Society 2000
Citation only
Epidemiology of Sarcopenia
Journal of Bone and Mineral Research 2016
Preprint · OA
Identification of Senescent Cells in the Bone Microenvironment
Nature Reviews Endocrinology 2020
Preprint · OA
The role of cellular senescence in ageing and endocrine disease
Endocrinology and Metabolism Clinics of North America 2005
Citation only
Pathophysiology of Age-Related Bone Loss and Osteoporosis
Cell 2024
Open access · CC-BY
Guidelines for minimal information on cellular senescence experimentation in vivo
Journal of Clinical Investigation 2008
Open access · OA
Building bone to reverse osteoporosis and repair fractures
The Annual Review of Pharmacology and Toxicology 2020
Open access · OA
Senolytic Drugs: Reducing Senescent Cell Viability to Extend Health Span
Bone 2019
Open access · OA
Cellular senescence in bone
Trends in Molecular Medicine 2020
Preprint · OA
Reducing Senescent Cell Burden in Aging and Disease
Journal of Bone and Mineral Research 2020
Open access · OA
Targeted Reduction of Senescent Cell Burden Alleviates Focal Radiotherapy-Related Bone Loss
Journal of Bone and Mineral Research 2019
Open access · OA
Independent Roles of Estrogen Deficiency and Cellular Senescence in the Pathogenesis of Osteoporosis: Evidence in Young Adult Mice and Older Humans
Nature Medicine 2024
Preprint · OA
Effects of intermittent senolytic therapy on bone metabolism in postmenopausal women: a phase 2 randomized controlled trial
EBioMedicine 2022
Open access · CC-BY
Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans
Journal of Clinical Investigation 2022
Open access · CC-BY
Cellular senescence and the skeleton: pathophysiology and therapeutic implications
Journal of Periodontology 2020
Preprint · OA
Senescent cells exacerbate chronic inflammation and contribute to periodontal disease progression in old mice
eLife 2021
Open access · CC-BY
Modulation of fracture healing by the transient accumulation of senescent cells
EBioMedicine 2020
Open access · CC-BY
Corrigendum to ‘Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease’ EBioMedicine 47 (2019) 446–456
Current Osteoporosis Reports 2020
Preprint · OA
Osteocyte Cellular Senescence
bioRxiv (Cold Spring Harbor Laboratory) 2021
Preprint · OA
A New Gene Set Identifies Senescent Cells and Predicts Senescence-Associated Pathways Across Tissues
Nature Communications 2023
Open access · CC-BY
Multiparametric senescent cell phenotyping reveals targets of senolytic therapy in the aged murine skeleton
Journal of the American Geriatrics Society 2021
Open access · CC-BY
Fisetin for COVID ‐19 in skilled nursing facilities: Senolytic trials in the COVID era
Journal of Bone and Mineral Research 2020
Open access · OA
Bone Marrow Adiposity in Models of Radiation- and Aging-Related Bone Loss Is Dependent on Cellular Senescence
Nature Aging 2023
Preprint · OA
Senescent cells, senolytics and tissue repair: the devil may be in the dosing
Elsevier eBooks 2013
Citation only
Estrogen Deficiency, Postmenopausal Osteoporosis, and Age-Related Bone Loss
The Journals of Gerontology Series A 2023
Open access · CC0
Drugs Targeting Mechanisms of Aging to Delay Age-Related Disease and Promote Healthspan: Proceedings of a National Institute on Aging Workshop
bioRxiv (Cold Spring Harbor Laboratory) 2023
Preprint · CC-BY
Distinct secretomes in p16- and p21- positive senescent cells across tissues
Aging Cell 2025
Open access · CC-BY
Characterization of Human Senescent Cell Biomarkers for Clinical Trials
Cell Metabolism 2025
Preprint · OA
Endothelial senescent-cell-specific clearance alleviates metabolic dysfunction in obese mice
bioRxiv (Cold Spring Harbor Laboratory) 2021
Preprint · CC-BY
Modulation of fracture healing by the transient accumulation of senescent cells
EMBO Molecular Medicine 2026
Open access · CC-BY
Tomatidine is a senotherapeutic compound that improves cognitive function and reduces cellular senescence in aged mice
Journal of Clinical Investigation 2024
Open access · CC-BY
A pipeline for senolytics
Research Square 2022
Preprint · CC-BY
Sub-lethal apoptotic stress enables mtDNA release during senescence and drives the SASP
bioRxiv (Cold Spring Harbor Laboratory) 2023
Preprint · CC-BY
Multiparametric senescent cell phenotyping reveals CD24 osteolineage cells as targets of senolytic therapy in the aged murine skeleton
Elsevier eBooks 2021
Citation only
Osteoporosis and bone loss
International Journal of Molecular Sciences 2025
Open access · CC-BY
Senolytic Treatment Improves Responsiveness to Mechanical Loading in the Skeleton of Aged Mice
medRxiv 2024
Preprint · OA
Characterization of human senescent cell biomarkers for clinical trials
Journal of the Endocrine Society 2024
Open access · CC-BY
6612 Both Overt And Mild Hypercortisolism Accelerate Biological Aging
bioRxiv (Cold Spring Harbor Laboratory) 2025
Preprint · OA