Shin‐ichiro Imai

Nature · 2000

◌ Citation only

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

▲ 3,475

npj Aging and Mechanisms of Disease · 2016

⊕ Open access · CC-BY

It takes two to tango: NAD+ and sirtuins in aging/longevity control

▲ 397

Aging Cell · 2016

⊕ Open access · CC-BY

Nicotinamide mononucleotide supplementation reverses vascular dysfunction and oxidative stress with aging in mice

▲ 397

Trends in Pharmacological Sciences · 2010

⊕ Open access · OA

Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases

▲ 387

Nature Metabolism · 2018

◌ Citation only

Slc12a8 is a nicotinamide mononucleotide transporter

▲ 280

Journal of Neuroscience · 2010

⊕ Open access · OA

SIRT1 Promotes the Central Adaptive Response to Diet Restriction through Activation of the Dorsomedial and Lateral Nuclei of the Hypothalamus

▲ 237

Cell Reports · 2016

⊕ Open access · CC-BY

NAMPT-Mediated NAD+ Biosynthesis in Adipocytes Regulates Adipose Tissue Function and Multi-organ Insulin Sensitivity in Mice

▲ 215

Cell Reports · 2016

⊕ Open access · CC-BY

NAMPT-Mediated NAD+ Biosynthesis Is Essential for Vision In Mice

▲ 193

Endocrine Journal · 2019

⊕ Open access · OA

Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men

▲ 191

F1000Research · 2018

⊕ Open access · CC-BY

NAD+ biosynthesis, aging, and disease

▲ 180

npj Systems Biology and Applications · 2016

⊕ Open access · CC-BY

The NAD World 2.0: the importance of the inter-tissue communication mediated by NAMPT/NAD+/SIRT1 in mammalian aging and longevity control

▲ 95

Nature Communications · 2014

⊕ Open access · OA

Systemic regulation of mammalian ageing and longevity by brain sirtuins

▲ 65

Aging Cell · 2020

⊕ Open access · CC-BY

SS‐31 and NMN: Two paths to improve metabolism and function in aged hearts

▲ 61

npj Aging and Mechanisms of Disease · 2018

⊕ Open access · CC-BY

CA1 Nampt knockdown recapitulates hippocampal cognitive phenotypes in old mice which nicotinamide mononucleotide improves

▲ 56

Cell Metabolism · 2024

⊕ Open access · CC-BY

DMHPpp1r17 neurons regulate aging and lifespan in mice through hypothalamic-adipose inter-tissue communication

▲ 41

npj Aging · 2025

⊕ Open access · CC-BY

NAD World 3.0: the importance of the NMN transporter and eNAMPT in mammalian aging and longevity control

▲ 21