Sebastian J. Hofer

Cell Reports · 2021

⊕ Open access · CC-BY

Dietary spermidine improves cognitive function

▲ 214

EMBO Molecular Medicine · 2021

⊕ Open access · CC-BY

The ups and downs of caloric restriction and fasting: from molecular effects to clinical application

▲ 206

Nature Communications · 2019

⊕ Open access · CC-BY

The flavonoid 4,4′-dimethoxychalcone promotes autophagy-dependent longevity across species

▲ 140

Nature Cell Biology · 2024

⊕ Open access · CC-BY

Spermidine is essential for fasting-mediated autophagy and longevity

▲ 140

FEMS Yeast Research · 2018

⊕ Open access · CC-BY

Yeast as a tool to identify anti-aging compounds

▲ 130

Annual Review of Nutrition · 2020

⊕ Open access · OA

Nutritional Aspects of Spermidine

▲ 112

Frontiers in Nutrition · 2021

⊕ Open access · CC-BY

Caloric Restriction Mimetics in Nutrition and Clinical Trials

▲ 109

Circulation · 2022

⊕ Open access · CC-BY

Fine-Tuning Cardiac Insulin-Like Growth Factor 1 Receptor Signaling to Promote Health and Longevity

▲ 106

JAMA Network Open · 2022

⊕ Open access · CC-BY

Effects of Spermidine Supplementation on Cognition and Biomarkers in Older Adults With Subjective Cognitive Decline

▲ 91

Autophagy · 2021

⊕ Open access · CC-BY

Spermidine-induced hypusination preserves mitochondrial and cognitive function during aging

▲ 83

EMBO Molecular Medicine · 2019

⊕ Open access · OA

3,4‐Dimethoxychalcone induces autophagy through activation of the transcription factors TFE3 and TFEB

▲ 64

Cell Metabolism · 2020

⊕ Open access · OA

Alternate Day Fasting Improves Physiological and Molecular Markers of Aging in Healthy, Non-obese Humans

▲ 62

Journal of Biological Chemistry · 2019

⊕ Open access · CC-BY

Acetyl-CoA carboxylase 1–dependent lipogenesis promotes autophagy downstream of AMPK

▲ 56

Scientific Reports · 2019

⊕ Open access · CC-BY

Spermidine protects from age-related synaptic alterations at hippocampal mossy fiber-CA3 synapses

▲ 56

GeroScience · 2021

⊕ Open access · CC-BY

Novel aspects of age-protection by spermidine supplementation are associated with preserved telomere length

▲ 40

Autophagy · 2024

⊕ Open access · CC-BY

A surge in endogenous spermidine is essential for rapamycin-induced autophagy and longevity

▲ 20

Cell Stress · 2023

⊕ Open access · CC-BY

Molecular targets of spermidine: implications for cancer suppression

▲ 19