Author
Riekelt H. Houtkooper
- Indexed works
- 30
- Total citations
- 9,195
- Active years
- 13
Collaborators
Works in the record
Nature Reviews Molecular Cell Biology 2012
Preprint · OA
Sirtuins as regulators of metabolism and healthspan
Cell 2013
Open access · OA
The NAD+/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling
Nature 2013
Preprint · OA
Mitonuclear protein imbalance as a conserved longevity mechanism
Endocrine Reviews 2010
Open access · OA
The Secret Life of NAD+: An Old Metabolite Controlling New Metabolic Signaling Pathways
Endocrine Reviews 2018
Open access · CC-BY
Metabolic Flexibility as an Adaptation to Energy Resources and Requirements in Health and Disease
Scientific Reports 2011
Open access · CC-BY
The metabolic footprint of aging in mice
Mechanisms of Ageing and Development 2020
Open access · CC-BY
Mitochondrial fission and fusion: A dynamic role in aging and potential target for age-related disease
Experimental & Molecular Medicine 2023
Open access · CC-BY
Mitochondria-associated programmed cell death as a therapeutic target for age-related disease
EMBO Molecular Medicine 2021
Open access · CC-BY
NAD+ homeostasis in human health and disease
Nature Protocols 2016
Preprint · CC-BY
A screening-based platform for the assessment of cellular respiration in Caenorhabditis elegans
American Journal of Clinical Nutrition 2020
Open access · CC-BY
Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans
Human Reproduction 2023
Open access · CC-BY
Human ovarian aging is characterized by oxidative damage and mitochondrial dysfunction
Molecular Metabolism 2019
Open access · CC-BY
A reduced form of nicotinamide riboside defines a new path for NAD+ biosynthesis and acts as an orally bioavailable NAD+ precursor
Cell Metabolism 2020
Open access · OA
A Conserved Mito-Cytosolic Translational Balance Links Two Longevity Pathways
EMBO Molecular Medicine 2019
Open access · CC-BY
From molecular promise to preclinical results: HDAC inhibitors in the race for healthy aging drugs
The Journal of Cell Biology 2012
Open access · CC-BY
Exploring the therapeutic space around NAD+
Nature Aging 2022
Open access · OA
Healthy aging and muscle function are positively associated with NAD+ abundance in humans
Frontiers in Cell and Developmental Biology 2020
Open access · CC-BY
Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction
Experimental Gerontology 2018
Open access · CC-BY
Identification of key pathways and metabolic fingerprints of longevity in C. elegans
The FASEB Journal 2021
Open access · CC-BY
Reduced nicotinamide mononucleotide is a new and potent NAD + precursor in mammalian cells and mice
Ageing Research Reviews 2022
Open access · CC-BY
Pharmaceutical and nutraceutical activation of FOXO3 for healthy longevity
Diabetologia 2019
Open access · CC-BY
NAD+ metabolism as a target for metabolic health: have we found the silver bullet?
Nature Communications 2022
Open access · CC-BY
The mouse metallomic landscape of aging and metabolism
Nature Communications 2023
Open access · CC-BY
Peripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models
Nature Aging 2025
Open access · OA
Emerging strategies, applications and challenges of targeting NAD+ in the clinic
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2017
Open access · CC-BY
Forward and reverse genetics approaches to uncover metabolic aging pathways in Caenorhabditis elegans
Journal of Nutrition 2021
Open access · OA
NAD+-Precursor Supplementation With L-Tryptophan, Nicotinic Acid, and Nicotinamide Does Not Affect Mitochondrial Function or Skeletal Muscle Function in Physically Compromised Older Adults
Biogerontology 2020
Open access · CC-BY
Identification of longevity compounds with minimized probabilities of side effects
Ageing Research Reviews 2023
Open access · CC-BY
Repurposing nucleoside reverse transcriptase inhibitors (NRTIs) to slow aging
Food Research International 2023
Preprint · OA