Author
Matt Kaeberlein
- Indexed works
- 54
- Total citations
- 12,886
- Active years
- 19
Collaborators
Works in the record
Nature 2000
Citation only
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
Genes & Development 1999
Open access · OA
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
Nature 2013
Preprint · OA
mTOR is a key modulator of ageing and age-related disease
Cell 2023
Open access · OA
Biomarkers of aging for the identification and evaluation of longevity interventions
Nature 2009
Preprint · OA
Histone H4 lysine 16 acetylation regulates cellular lifespan
eLife 2016
Open access · CC-BY
Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice
Cell Cycle 2009
Open access · OA
A molecular mechanism of chronological aging in yeast
PLoS Genetics 2007
Open access · CC-BY
Recent Developments in Yeast Aging
Genes & Development 2015
Preprint · CC-BY
H3K36 methylation promotes longevity by enhancing transcriptional fidelity
Nature Communications 2014
Open access · OA
Activation of the mitochondrial unfolded protein response does not predict longevity in Caenorhabditis elegans
Journal of Visualized Experiments 2009
Open access · OA
Measuring Caenorhabditis elegans Life Span on Solid Media
GeroScience 2017
Open access · OA
A randomized controlled trial to establish effects of short-term rapamycin treatment in 24 middle-aged companion dogs
F1000Prime Reports 2013
Open access · OA
Longevity and aging
The Journals of Gerontology Series A 2008
Open access · OA
A Method for High-Throughput Quantitative Analysis of Yeast Chronological Life Span
Cold Spring Harbor Perspectives in Medicine 2015
Preprint · OA
Biochemical Genetic Pathways that Modulate Aging in Multiple Species: Figure 1.
PLoS Genetics 2014
Open access · CC-BY
Enhanced Longevity by Ibuprofen, Conserved in Multiple Species, Occurs in Yeast through Inhibition of Tryptophan Import
Cell Cycle 2011
Open access · OA
A genomic analysis of chronological longevity factors in budding yeast
Frontiers in Genetics 2015
Open access · CC-BY
Dose-dependent effects of mTOR inhibition on weight and mitochondrial disease in mice
Journal of Visualized Experiments 2009
Open access · OA
Quantifying Yeast Chronological Life Span by Outgrowth of Aged Cells
The Journals of Gerontology Series A 2013
Open access · OA
Life-Span Extension From Hypoxia in Caenorhabditis elegans Requires Both HIF-1 and DAF-16 and Is Antagonized by SKN-1
PLoS Biology 2015
Open access · CC-BY
Why Is Aging Conserved and What Can We Do about It?
PLoS Genetics 2014
Open access · CC-BY
Lifespan Extension Conferred by Endoplasmic Reticulum Secretory Pathway Deficiency Requires Induction of the Unfolded Protein Response
The Lancet Healthy Longevity 2023
Open access · CC-BY
ExplaiNAble BioLogical Age (ENABL Age): an artificial intelligence framework for interpretable biological age
PLoS ONE 2011
Open access · CC-BY
Composition and Acidification of the Culture Medium Influences Chronological Aging Similarly in Vineyard and Laboratory Yeast
Aging Cell 2022
Open access · CC-BY
Lifespan benefits for the combination of rapamycin plus acarbose and for captopril in genetically heterogeneous mice
Translational Medicine of Aging 2017
Open access · CC-BY
Translational geroscience: A new paradigm for 21st century medicine
GeroScience 2023
Open access · OA
Evaluation of off-label rapamycin use to promote healthspan in 333 adults
Oncotarget 2016
Open access · CC-BY
Rapamycin in aging and disease: maximizing efficacy while minimizing side effects
BMC Bioinformatics 2010
Open access · CC-BY
YODA: Software to facilitate high-throughput analysis of chronological life span, growth rate, and survival in budding yeast
Nature Communications 2021
Open access · CC-BY
Inactivating histone deacetylase HDA promotes longevity by mobilizing trehalose metabolism
Kidney International 2018
Open access · OA
mTOR inhibitors may benefit kidney transplant recipients with mitochondrial diseases
Oncotarget 2016
Open access · CC-BY
Rapamycin enhances survival in a Drosophila model of mitochondrial disease
Scientifica 2013
Open access · CC-BY
mTOR Inhibition: From Aging to Autism and Beyond
Cell Cycle 2011
Open access · OA
Quantitative evidence for early life fitness defects from 32 longevity-associated alleles in yeast
Frontiers in Genetics 2015
Open access · CC-BY
Sorbitol treatment extends lifespan and induces the osmotic stress response in Caenorhabditis elegans
Aging Cell 2016
Open access · CC-BY
Aneuploidy shortens replicative lifespan in Saccharomyces cerevisiae
Translational Medicine of Aging 2018
Open access · CC-BY
Translational geroscience: From invertebrate models to companion animal and human interventions
Cell Metabolism 2014
Open access · OA
Rejuvenation: It’s in Our Blood
Proceedings of the National Academy of Sciences 2019
Open access · OA
Defining the impact of mutation accumulation on replicative lifespan in yeast using cancer-associated mutator phenotypes
F1000Research 2013
Open access · CC-BY
Buffering the pH of the culture medium does not extend yeast replicative lifespan
AGE 2015
Open access · OA
PMT1 deficiency enhances basal UPR activity and extends replicative lifespan of Saccharomyces cerevisiae
npj Aging and Mechanisms of Disease 2015
Open access · CC-BY
Defining molecular basis for longevity traits in natural yeast isolates
Aging Cell 2007
Citation only
Does resveratrol activate yeast Sir2 in vivo?
Cell Metabolism 2008
Open access · OA
The Ongoing Saga of Sirtuins and Aging
Nature Metabolism 2023
Preprint · OA
Acarbose suppresses symptoms of mitochondrial disease in a mouse model of Leigh syndrome
Cell Reports 2022
Open access · CC-BY
Deficiency of the RNA-binding protein Cth2 extends yeast replicative lifespan by alleviating its repressive effects on mitochondrial function
Ageing Research Reviews 2024
Preprint · OA
The impact of short-lived controls on the interpretation of lifespan experiments and progress in geroscience – Through the lens of the “900-day rule”
Cell 2015
Open access · OA
Fertile Waters for Aging Research
GeroScience 2023
Open access · CC-BY
Genetic perturbation of mitochondrial function reveals functional role for specific mitonuclear genes, metabolites, and pathways that regulate lifespan
bioRxiv (Cold Spring Harbor Laboratory) 2020
Preprint · CC-BY