Author
Matt Kaeberlein
- Indexed works
- 61
- Total citations
- 15,403
- Active years
- 22
Collaborators
Works in the record
Nature 2000
Citation only
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
Genes & Development 1999
Open access · OA
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
Nature 2013
Citation only
mTOR is a key modulator of ageing and age-related disease
Genes & Development 2006
Preprint · OA
Extension of chronological life span in yeast by decreased TOR pathway signaling
Journal of Biological Chemistry 2005
Open access · CC-BY
Substrate-specific Activation of Sirtuins by Resveratrol
Nature 2009
Preprint · OA
Histone H4 lysine 16 acetylation regulates cellular lifespan
Cell 2023
Preprint · OA
Biomarkers of aging for the identification and evaluation of longevity interventions
eLife 2016
Open access · CC-BY
Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice
PLoS Biology 2004
Open access · CC-BY
Sir2-Independent Life Span Extension by Calorie Restriction in Yeast
PLoS Genetics 2011
Open access · CC-BY
Elevated Proteasome Capacity Extends Replicative Lifespan in Saccharomyces cerevisiae
PLoS Genetics 2007
Open access · CC-BY
Recent Developments in Yeast Aging
Genes & Development 2015
Preprint · CC-BY
H3K36 methylation promotes longevity by enhancing transcriptional fidelity
Nature Communications 2014
Open access · OA
Activation of the mitochondrial unfolded protein response does not predict longevity in Caenorhabditis elegans
Journal of Visualized Experiments 2009
Open access · OA
Measuring <em>Caenorhabditis elegans</em> Life Span on Solid Media
PLoS Genetics 2005
Open access · CC-BY
Increased Life Span due to Calorie Restriction in Respiratory-Deficient Yeast
GeroScience 2017
Preprint · OA
A randomized controlled trial to establish effects of short-term rapamycin treatment in 24 middle-aged companion dogs
BMC Developmental Biology 2008
Open access · CC-BY
Age- and calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans
F1000Prime Reports 2013
Open access · OA
Longevity and aging
The Journals of Gerontology Series A 2008
Open access · OA
A Method for High-Throughput Quantitative Analysis of Yeast Chronological Life Span
Cold Spring Harbor Perspectives in Medicine 2015
Preprint · OA
Biochemical Genetic Pathways that Modulate Aging in Multiple Species: Figure 1.
PLoS Genetics 2013
Open access · CC-BY
A Natural Polymorphism in rDNA Replication Origins Links Origin Activation with Calorie Restriction and Lifespan
Aging Cell 2006
Open access · OA
Sirtuin‐independent effects of nicotinamide on lifespan extension from calorie restriction in yeast
Nature Communications 2015
Open access · OA
Transcription errors induce proteotoxic stress and shorten cellular lifespan
PLoS Genetics 2014
Open access · CC-BY
Enhanced Longevity by Ibuprofen, Conserved in Multiple Species, Occurs in Yeast through Inhibition of Tryptophan Import
Frontiers in Genetics 2015
Open access · CC-BY
Dose-dependent effects of mTOR inhibition on weight and mitochondrial disease in mice
Journal of Visualized Experiments 2009
Open access · OA
Quantifying Yeast Chronological Life Span by Outgrowth of Aged Cells
The Journals of Gerontology Series A 2013
Open access · OA
Life-Span Extension From Hypoxia in Caenorhabditis elegans Requires Both HIF-1 and DAF-16 and Is Antagonized by SKN-1
PLoS Genetics 2014
Open access · CC-BY
Lifespan Extension Conferred by Endoplasmic Reticulum Secretory Pathway Deficiency Requires Induction of the Unfolded Protein Response
PLoS Biology 2015
Open access · CC-BY
Why Is Aging Conserved and What Can We Do about It?
PLoS ONE 2011
Open access · CC-BY
Composition and Acidification of the Culture Medium Influences Chronological Aging Similarly in Vineyard and Laboratory Yeast
The Lancet Healthy Longevity 2023
Open access · CC-BY
ExplaiNAble BioLogical Age (ENABL Age): an artificial intelligence framework for interpretable biological age
Aging Cell 2022
Open access · CC-BY
Lifespan benefits for the combination of rapamycin plus acarbose and for captopril in genetically heterogeneous mice
Translational Medicine of Aging 2017
Open access · CC-BY
Translational geroscience: A new paradigm for 21st century medicine
BMC Bioinformatics 2010
Open access · CC-BY
YODA: Software to facilitate high-throughput analysis of chronological life span, growth rate, and survival in budding yeast
Oncotarget 2016
Open access · CC-BY
Rapamycin in aging and disease: maximizing efficacy while minimizing side effects
GeroScience 2023
Open access · OA
Evaluation of off-label rapamycin use to promote healthspan in 333 adults
Nature Communications 2021
Open access · CC-BY
Inactivating histone deacetylase HDA promotes longevity by mobilizing trehalose metabolism
Kidney International 2018
Open access · OA
mTOR inhibitors may benefit kidney transplant recipients with mitochondrial diseases
Oncotarget 2016
Open access · CC-BY
Rapamycin enhances survival in a<i>Drosophila</i>model of mitochondrial disease
Scientifica 2013
Open access · CC-BY
mTOR Inhibition: From Aging to Autism and Beyond
Frontiers in Genetics 2015
Open access · CC-BY
Sorbitol treatment extends lifespan and induces the osmotic stress response in Caenorhabditis elegans
eLife 2019
Open access · CC-BY
DNA damage checkpoint activation impairs chromatin homeostasis and promotes mitotic catastrophe during aging
Cell Metabolism 2014
Open access · OA
Rejuvenation: It’s in Our Blood
GeroScience 2023
Preprint · OA
Preservation of mitochondrial membrane potential is necessary for lifespan extension from dietary restriction
F1000Research 2013
Open access · CC-BY
Buffering the pH of the culture medium does not extend yeast replicative lifespan
Proceedings of the National Academy of Sciences 2019
Open access · OA
Defining the impact of mutation accumulation on replicative lifespan in yeast using cancer-associated mutator phenotypes
AGE 2015
Citation only
PMT1 deficiency enhances basal UPR activity and extends replicative lifespan of Saccharomyces cerevisiae
npj Aging and Mechanisms of Disease 2015
Open access · CC-BY
Defining molecular basis for longevity traits in natural yeast isolates
Cell Metabolism 2008
Open access · OA
The Ongoing Saga of Sirtuins and Aging
Aging Cell 2007
Open access · OA