Marian Beekman

Nature Communications · 2016

⊕ Open access · CC-BY

Genetic and environmental influences interact with age and sex in shaping the human methylome

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Nature Communications · 2019

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A meta-analysis of genome-wide association studies identifies multiple longevity genes

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Aging Cell · 2005

⊕ Open access · OA

Reduced insulin/IGF‐1 signalling and human longevity

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Scientific Reports · 2017

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Subclass-specific IgG glycosylation is associated with markers of inflammation and metabolic health

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AGE · 2011

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Gene set analysis of GWAS data for human longevity highlights the relevance of the insulin/IGF-1 signaling and telomere maintenance pathways

▲ 126

Nature Communications · 2018

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Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait

▲ 114

The Journals of Gerontology Series A · 2023

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Epigenetic and Metabolomic Biomarkers for Biological Age: A Comparative Analysis of Mortality and Frailty Risk

▲ 84

Aging Cell · 2016

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Genomewide meta‐analysis identifies loci associated with IGF ‐I and IGFBP ‐3 levels with impact on age‐related traits

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Aging · 2009

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Human insulin/IGF-1 and familial longevity at middle age

▲ 71

Aging Cell · 2020

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Longevity Relatives Count score identifies heritable longevity carriers and suggests case improvement in genetic studies

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European Journal of Epidemiology · 2024

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The AccelerAge framework: a new statistical approach to predict biological age based on time-to-event data

▲ 14

EBioMedicine · 2024

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NMR metabolomics-guided DNA methylation mortality predictors

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Immunity & Ageing · 2025

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Extreme MetaboHealth scores in three cohort studies associate with plasma protein markers for inflammation and cholesterol transport

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Cell Reports Methods · 2026

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ProtFI, an efficient frailty-trained proteomics-based biomarker of aging, robustly predicts age-related decline

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GeroScience · 2026

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Low genetic risk for coronary artery disease underlies multigenerational longevity and healthy aging

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bioRxiv (Cold Spring Harbor Laboratory) · 2026

⊕ Preprint · CC-BY

Rare genetic variants in the IIS/mTOR signalling pathway identified in exceptionally long-lived individuals show shared in vitro effects associated with lifespan across species

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