Author
Linda Partridge
- Indexed works
- 79
- Total citations
- 35,344
- Active years
- 26
Collaborators
Works in the record
Cell 2013
Open access · OA
The Hallmarks of Aging
Cell 2023
Open access · OA
Hallmarks of aging: An expanding universe
Nature Aging 2021
Open access · OA
Autophagy in healthy aging and disease
Cell Metabolism 2010
Open access · CC-BY
Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster
PLoS Genetics 2010
Open access · CC-BY
Molecular Evolution and Functional Characterization of Drosophila Insulin-Like Peptides
The FASEB Journal 2007
Citation only
Evidence for lifespan extension and delayed age–related biomarkers in insulin receptor substrate 1 null mice
PLoS Biology 2005
Open access · CC-BY
Calories Do Not Explain Extension of Life Span by Dietary Restriction in Drosophila
Nature Reviews Drug Discovery 2020
Preprint · OA
The quest to slow ageing through drug discovery
Proceedings of the Royal Society B Biological Sciences 1996
Citation only
Female fitness in Drosophila melanogaster : an interaction between the effect of nutrition and of encounter rate with males
Trends in Cell Biology 2004
Citation only
The interaction between FOXO and SIRT1: tipping the balance towards survival
Experimental Gerontology 2010
Open access · CC-BY
Ageing in Drosophila: The role of the insulin/Igf and TOR signalling network
PLoS ONE 2009
Open access · CC-BY
Quantification of Food Intake in Drosophila
Evolution 1992
Citation only
DIRECT AND CORRELATED RESPONSES TO SELECTION ON AGE AT REPRODUCTION IN<i>DROSOPHILA MELANOGASTER</i>
Nature Communications 2017
Open access · CC-BY
Small nucleoli are a cellular hallmark of longevity
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2017
Open access · OA
Drosophila as a model for ageing
eLife 2016
Open access · CC-BY
Sex difference in pathology of the ageing gut mediates the greater response of female lifespan to dietary restriction
BMC Biology 2018
Open access · CC-BY
Horizons in the evolution of aging
Cell 2015
Open access · CC-BY
The Ras-Erk-ETS-Signaling Pathway Is a Drug Target for Longevity
Cell Metabolism 2017
Open access · CC-BY
Matching Dietary Amino Acid Balance to the In Silico-Translated Exome Optimizes Growth and Reproduction without Cost to Lifespan
Genome biology 2017
Open access · CC-BY
Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism
Biochemical Journal 2009
Citation only
Insulin/IGF-like signalling, the central nervous system and aging
Cell 2023
Preprint · OA
Atlas of the aging mouse brain reveals white matter as vulnerable foci
Aging Cell 2011
Preprint · CC-BY
dFOXO‐independent effects of reduced insulin‐like signaling in Drosophila
Nature 2023
Open access · CC-BY
Ageing-associated changes in transcriptional elongation influence longevity
PLoS ONE 2012
Open access · CC-BY
Activation of AMPK by the Putative Dietary Restriction Mimetic Metformin Is Insufficient to Extend Lifespan in Drosophila
PLoS ONE 2008
Open access · CC-BY
Reduction of DILP2 in Drosophila Triages a Metabolic Phenotype from Lifespan Revealing Redundancy and Compensation among DILPs
Cell Reports 2016
Open access · CC-BY
Lithium Promotes Longevity through GSK3/NRF2-Dependent Hormesis
Molecular and Cellular Endocrinology 2008
Citation only
Endocrine regulation of aging and reproduction in Drosophila
Journal of Neuroscience 2016
Open access · CC-BY
ADrosophilaModel of Neuronopathic Gaucher Disease Demonstrates Lysosomal-Autophagic Defects and Altered mTOR Signalling and Is Functionally Rescued by Rapamycin
Annual Review of Biochemistry 2016
Open access · OA
Dietary Protein, Metabolism, and Aging
Current Biology 2018
Open access · CC-BY
Short-Term, Intermittent Fasting Induces Long-Lasting Gut Health and TOR-Independent Lifespan Extension
PLoS Genetics 2007
Open access · CC-BY
Dietary Restriction in Drosophila: Delayed Aging or Experimental Artefact?
Experimental Gerontology 2004
Citation only
Metabolic rate is not reduced by dietary-restriction or by lowered insulin/IGF-1 signalling and is not correlated with individual lifespan in Drosophila melanogaster
Molecular Systems Biology 2011
Open access · CC-BY
Genome‐wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling
Nature Aging 2022
Open access · CC-BY
Long-lasting geroprotection from brief rapamycin treatment in early adulthood by persistently increased intestinal autophagy
PLoS ONE 2008
Open access · CC-BY
Effect of a Standardised Dietary Restriction Protocol on Multiple Laboratory Strains of Drosophila melanogaster
The Journals of Gerontology Series A 2015
Open access · CC-BY
Longevity GWAS Using theDrosophilaGenetic Reference Panel
PLoS Genetics 2007
Open access · CC-BY
No Influence of Indy on Lifespan in Drosophila after Correction for Genetic and Cytoplasmic Background Effects
PLoS ONE 2011
Open access · CC-BY
Replication of Extended Lifespan Phenotype in Mice with Deletion of Insulin Receptor Substrate 1
Experimental Gerontology 2004
Citation only
Lifespan extension by dietary restriction in female Drosophila melanogaster is not caused by a reduction in vitellogenesis or ovarian activity
Proceedings of the National Academy of Sciences 2019
Open access · CC-BY
A triple drug combination targeting components of the nutrient-sensing network maximizes longevity
Nature Communications 2021
Open access · CC-BY
Regulation of the one carbon folate cycle as a shared metabolic signature of longevity
Aging Cell 2010
Open access · OA
Biomarkers of aging in Drosophila
The Journals of Gerontology Series A 2005
Citation only
Counting the Calories: The Role of Specific Nutrients in Extension of Life Span by Food Restriction
PLoS Genetics 2010
Open access · CC-BY
Regulation of Lifespan, Metabolism, and Stress Responses by the Drosophila SH2B Protein, Lnk
Nature Aging 2022
Open access · CC-BY
Sexual identity of enterocytes regulates autophagy to determine intestinal health, lifespan and responses to rapamycin
eLife 2021
Open access · CC-BY
A TORC1-histone axis regulates chromatin organisation and non-canonical induction of autophagy to ameliorate ageing
PLoS Genetics 2014
Open access · CC-BY
Interplay of dFOXO and Two ETS-Family Transcription Factors Determines Lifespan in Drosophila melanogaster
PLoS Genetics 2020
Open access · CC-BY
Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila
Proceedings of the Royal Society B Biological Sciences 2010
Open access · CC-BY