Christine A. Sedore

Nature Communications 2017

Open access · CC-BY

Impact of genetic background and experimental reproducibility on identifying chemical compounds with robust longevity effects

▲ 157

Aging Cell 2021

Open access · CC-BY

Metformin treatment of diverse Caenorhabditis species reveals the importance of genetic background in longevity and healthspan extension outcomes

▲ 46

Aging 2024

Open access · CC-BY

The coupling between healthspan and lifespan in Caenorhabditis depends on complex interactions between compound intervention and genetic background

▲ 21

GeroScience 2023

Open access · CC-BY

Antioxidants green tea extract and nordihydroguaiaretic acid confer species and strain-specific lifespan and health effects in Caenorhabditis nematodes

▲ 16

GeroScience 2025

Open access · CC0

NIA Caenorhabditis Intervention Testing Program: identification of robust and reproducible pharmacological interventions that promote longevity across experimentally accessible, genetically diverse populations

▲ 11

bioRxiv (Cold Spring Harbor Laboratory) 2022

Preprint · CC-BY

The coupling between healthspan and lifespan in Caenorhabditis depends on complex interactions between compound intervention and genetic background

▲ 3

eLife 2024

Preprint · CC-BY

Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically diverse Caenorhabditis nematodes

▲ 1

bioRxiv (Cold Spring Harbor Laboratory) 2021

Preprint · CC-BY

Antioxidants green tea extract and nordihydroguaiaretic acid confer species and strain specific lifespan and health effects in Caenorhabditis nematodes

▲ 1

eLife 2025

Open access · CC-BY

Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically diverse Caenorhabditis nematodes

▲ 1

PubMed Central 2026

Preprint · CC-BY

Caenorhabditis Intervention Testing Program: the putative mTOR inhibitors Cinnarizine and Meclizine do not extend lifespan in C. elegans

▲ 0

Innovation in Aging 2022

Open access · CC-BY

ANTI-AGING COMPOUNDS METFORMIN AND THIOFLAVIN T CAN ACT ON GENETICALLY DIVERSE, PROTEOSTASIS-COMPROMISED STRAINS

▲ 0

Collaborators

Works in the record

Impact of genetic background and experimental reproducibility on identifying chemical compounds with robust longevity effects

Metformin treatment of diverse Caenorhabditis species reveals the importance of genetic background in longevity and healthspan extension outcomes

The coupling between healthspan and lifespan in Caenorhabditis depends on complex interactions between compound intervention and genetic background

Antioxidants green tea extract and nordihydroguaiaretic acid confer species and strain-specific lifespan and health effects in Caenorhabditis nematodes

NIA Caenorhabditis Intervention Testing Program: identification of robust and reproducible pharmacological interventions that promote longevity across experimentally accessible, genetically diverse populations

The coupling between healthspan and lifespan in Caenorhabditis depends on complex interactions between compound intervention and genetic background

Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically diverse Caenorhabditis nematodes

Antioxidants green tea extract and nordihydroguaiaretic acid confer species and strain specific lifespan and health effects in Caenorhabditis nematodes

Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically diverse Caenorhabditis nematodes

Caenorhabditis Intervention Testing Program: the putative mTOR inhibitors Cinnarizine and Meclizine do not extend lifespan in C. elegans

ANTI-AGING COMPOUNDS METFORMIN AND THIOFLAVIN T CAN ACT ON GENETICALLY DIVERSE, PROTEOSTASIS-COMPROMISED STRAINS