Chen Y

Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026

Open access · OA

SPARC Drives Podocyte Mitochondrial Damage and Ferroptosis in Diabetic Kidney Disease Following Klotho Deficiency.

▲ 1

NPJ Regenerative medicine 2026

Open access · OA

Multi-omics profiling reveals systemic rejuvenation of the aged kidney through senolytic therapy.

▲ 1

Nature aging 2025

Citation only

Cerebrospinal fluid proteomic signatures in cognitively normal individuals identify distinct clusters linked to neurodegeneration.

▲ 1

International journal of molecular sciences 2026

Open access · OA

Mitochondrial Quality Control Imbalance in the Heterogeneity of Parkinson's Disease: From Selective Vulnerability to Stratified Transformation.

▲ 0

Nutrients 2026

Open access · OA

Effects of Nicotinamide Mononucleotide Supplementation on Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

▲ 0

MedComm 2026

Open access · OA

Targeting Mitochondria in Aging-Related Diseases: Therapeutic Potential and Obstacles.

▲ 0

Biogerontology 2026

Citation only

Dendrobium officinale leaf extract extends the mean lifespan in Caenorhabditis elegans via the DAF-16/SOD-3 axis.

▲ 0

Food & function 2026

Citation only

Bound polyphenols from carrot dietary fiber delay aging in <i>Caenorhabditis elegans</i> through the IIS pathway and metabolic remodeling.

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Journal of ethnopharmacology 2026

Citation only

Dendrobium officinale extends lifespan in yeast and Drosophila via context-dependent PI3K-AKT modulation.

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Frontiers in immunology 2026

Open access · OA

Chronic low-grade inflammation drives skeletal aging and neurocognitive decline: inflammaging as a central hub coupling bone-brain aging.

▲ 0

Frontiers in microbiology 2026

Open access · OA

Clinical translation of salivary MicroAge for understanding the oral-systemic connection in healthy longevity.

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International journal of surgery (London, England) 2026

Open access · OA

Integrated multi-omics identifies MCRS1 as a causal hub linking aging, metabolic syndrome, and breast cancer progression.

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Ecotoxicology and environmental safety 2026

Citation only

Life-cycle exposure to tris(2-butoxyethyl) phosphate at environmentally relevant concentrations induces progressive Parkinsonian-like neurodegeneration via lysosomal dysfunction in Caenorhabditis elegans.

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Aging cell 2026

Open access · OA

Inferring Gene Regulatory Network Architecture Underlying Complex Traits: An Integrative Analysis of Mutant Lifespan and Gene Expression Profiles Identifies Master Regulators and Key Functional Modules for Yeast Aging.

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Frontiers in microbiology 2026

Open access · OA

Pathogenic mechanisms and comprehensive therapeutic strategies of ovarian aging: targeting gut microbiota.

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International journal of molecular medicine 2026

Open access · OA

Dysregulation of the DNA repair‑immune axis: Targeted therapeutic strategies for autoimmune diseases (Review).

▲ 0

Journal of cell communication and signaling 2026

Open access · OA

Vitamin D receptor signaling in inflammatory senescence-associated skin aging: Mechanisms and therapeutic potentials.

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Aging and disease 2026

Citation only

Circadian Rhythm, Clock Genes and Osteoarthritis: The Dream of a Good Night's Sleep.

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2026

Preprint

Muscle-Specific Upregulation of Timeless Mediates Exercise-Induced Amelioration of Age-Related Circadian Rhythm Disruption and Cardiac Dysfunction in Drosophila

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International journal of molecular sciences 2026

Open access · OA

Circadian Rhythms in Acute Respiratory Distress Syndrome: Molecular Mechanisms and Therapeutic Implications.

▲ 0

Frontiers in immunology

Open access · OA

The role of the gut–lung axis in persistent inflammation and disease progression in chronic obstructive pulmonary disease: mechanistic evidence and therapeutic implications

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NPJ digital medicine 2026

Open access · OA

Proteomic clocks combined with deep learning phenotypes track eye aging and diseases.

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EBioMedicine 2026

Open access · OA

Proteomic organ-specific signatures, ageing traits, disease risks and genetic architecture in an East Asian population.

▲ 0

The journal of nutrition, health & aging 2026

Open access · OA

Impact of frailty phenotype on chronic disease accumulation and healthy life years lost: A multi-state analysis of the UK Biobank.

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Cells 2026

Open access · OA

Smooth Muscle Cell MAPK14 Promotes Vascular Calcification During Hyperlipidemic Aging.

▲ 0

International journal of molecular sciences 2026

Open access · OA

Effects and Therapeutic Strategies of Intra-Hepatic Cellular Senescence and Regeneration

▲ 0

Aging cell 2026

Open access · OA

Ginsenoside Rg3 Promotes Healthy Aging Through Phosphoinositide‐Associated Lysosomal Regulation in Caenorhabditis elegans

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Zoological research 2026

Citation only

Unlocking the secrets of naked mole-rat longevity.

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Bioscience, biotechnology, and biochemistry 2026

Citation only

Azelaic acid delays aging and prolongs lifespan via resisting oxidation stress mediated by IIS pathway coupling hsf-1 in C. elegans.

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Environmental science & technology 2026

Open access · OA

Aging of Urban Traffic Fine Particles Modulates Toxicity Mechanisms and Oxidative Stress Responses.

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Molecular biomedicine 2026

Open access · OA

The sirtuin family: from mechanisms to therapy.

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International journal of molecular sciences 2026

Open access · OA

Epigenetic Mechanisms in Neurodegenerative Diseases: From Genetic Regulation to Therapeutic Potential

▲ 0

International journal of molecular sciences 2026

Open access · OA

Epigenetic Mechanisms in Neurodegenerative Diseases: From Genetic Regulation to Therapeutic Potential.

▲ 0

Food research international (Ottawa, Ont.) 2025

Citation only

Polysaccharide from Ganoderma atrum delay senescence and enhance stress resistance through modulating IIS and MAPK pathway in Caenorhabditis elegans.

▲ 0

Frontiers in aging neuroscience

Open access · OA

Infection-related research in Parkinson’s disease: an exploratory trends analysis

▲ 0

International journal of molecular sciences 2025

Open access · OA

Apiin Promotes Healthy Aging in <i>C. elegans</i> Through Nutritional Activation of DAF-16/FOXO, Enhancing Fatty Acid Catabolism and Oxidative Stress Resistance.

▲ 0

BMC complementary medicine and therapies 2025

Open access · OA

Identification of active anti-aging ingredients from asparagus cochinchinensis based on the spectrum-effect relationship.

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Collaborators

Works in the record

SPARC Drives Podocyte Mitochondrial Damage and Ferroptosis in Diabetic Kidney Disease Following Klotho Deficiency.

Multi-omics profiling reveals systemic rejuvenation of the aged kidney through senolytic therapy.

Cerebrospinal fluid proteomic signatures in cognitively normal individuals identify distinct clusters linked to neurodegeneration.

Mitochondrial Quality Control Imbalance in the Heterogeneity of Parkinson's Disease: From Selective Vulnerability to Stratified Transformation.

Effects of Nicotinamide Mononucleotide Supplementation on Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Targeting Mitochondria in Aging-Related Diseases: Therapeutic Potential and Obstacles.

Dendrobium officinale leaf extract extends the mean lifespan in Caenorhabditis elegans via the DAF-16/SOD-3 axis.

Bound polyphenols from carrot dietary fiber delay aging in <i>Caenorhabditis elegans</i> through the IIS pathway and metabolic remodeling.

Dendrobium officinale extends lifespan in yeast and Drosophila via context-dependent PI3K-AKT modulation.

Chronic low-grade inflammation drives skeletal aging and neurocognitive decline: inflammaging as a central hub coupling bone-brain aging.

Clinical translation of salivary MicroAge for understanding the oral-systemic connection in healthy longevity.

Integrated multi-omics identifies MCRS1 as a causal hub linking aging, metabolic syndrome, and breast cancer progression.

Life-cycle exposure to tris(2-butoxyethyl) phosphate at environmentally relevant concentrations induces progressive Parkinsonian-like neurodegeneration via lysosomal dysfunction in Caenorhabditis elegans.

Inferring Gene Regulatory Network Architecture Underlying Complex Traits: An Integrative Analysis of Mutant Lifespan and Gene Expression Profiles Identifies Master Regulators and Key Functional Modules for Yeast Aging.

Pathogenic mechanisms and comprehensive therapeutic strategies of ovarian aging: targeting gut microbiota.

Dysregulation of the DNA repair‑immune axis: Targeted therapeutic strategies for autoimmune diseases (Review).

Vitamin D receptor signaling in inflammatory senescence-associated skin aging: Mechanisms and therapeutic potentials.

Circadian Rhythm, Clock Genes and Osteoarthritis: The Dream of a Good Night's Sleep.

Muscle-Specific Upregulation of Timeless Mediates Exercise-Induced Amelioration of Age-Related Circadian Rhythm Disruption and Cardiac Dysfunction in Drosophila

Circadian Rhythms in Acute Respiratory Distress Syndrome: Molecular Mechanisms and Therapeutic Implications.

The role of the gut–lung axis in persistent inflammation and disease progression in chronic obstructive pulmonary disease: mechanistic evidence and therapeutic implications

Proteomic clocks combined with deep learning phenotypes track eye aging and diseases.

Proteomic organ-specific signatures, ageing traits, disease risks and genetic architecture in an East Asian population.

Impact of frailty phenotype on chronic disease accumulation and healthy life years lost: A multi-state analysis of the UK Biobank.

Smooth Muscle Cell MAPK14 Promotes Vascular Calcification During Hyperlipidemic Aging.

Effects and Therapeutic Strategies of Intra-Hepatic Cellular Senescence and Regeneration

Ginsenoside Rg3 Promotes Healthy Aging Through Phosphoinositide‐Associated Lysosomal Regulation in Caenorhabditis elegans

Unlocking the secrets of naked mole-rat longevity.

Azelaic acid delays aging and prolongs lifespan via resisting oxidation stress mediated by IIS pathway coupling hsf-1 in C. elegans.

Aging of Urban Traffic Fine Particles Modulates Toxicity Mechanisms and Oxidative Stress Responses.

The sirtuin family: from mechanisms to therapy.

Epigenetic Mechanisms in Neurodegenerative Diseases: From Genetic Regulation to Therapeutic Potential

Epigenetic Mechanisms in Neurodegenerative Diseases: From Genetic Regulation to Therapeutic Potential.

Polysaccharide from Ganoderma atrum delay senescence and enhance stress resistance through modulating IIS and MAPK pathway in Caenorhabditis elegans.

Infection-related research in Parkinson’s disease: an exploratory trends analysis

Apiin Promotes Healthy Aging in <i>C. elegans</i> Through Nutritional Activation of DAF-16/FOXO, Enhancing Fatty Acid Catabolism and Oxidative Stress Resistance.

Identification of active anti-aging ingredients from asparagus cochinchinensis based on the spectrum-effect relationship.