Brian Onken

PLoS Genetics 2008

Open access · CC-BY

A Role for Autophagy in the Extension of Lifespan by Dietary Restriction in C. elegans

▲ 766

PLoS ONE 2010

Open access · CC-BY

Metformin Induces a Dietary Restriction–Like State and the Oxidative Stress Response to Extend C. elegans Healthspan via AMPK, LKB1, and SKN-1

▲ 683

Nature Communications 2017

Open access · CC-BY

Impact of genetic background and experimental reproducibility on identifying chemical compounds with robust longevity effects

▲ 138

PLoS Genetics 2013

Open access · CC-BY

Deletion of microRNA-80 Activates Dietary Restriction to Extend C. elegans Healthspan and Lifespan

▲ 80

Journal of Agricultural and Food Chemistry 2014

Citation only

Mechanism of Longevity Extension of<i>Caenorhabditis elegans</i>Induced by Pentagalloyl Glucose Isolated from Eucalyptus Leaves

▲ 68

Aging Cell 2021

Open access · CC-BY

Metformin treatment of diverse Caenorhabditis species reveals the importance of genetic background in longevity and healthspan extension outcomes

▲ 42

PLoS Genetics 2020

Open access · CC-BY

Gluconeogenesis and PEPCK are critical components of healthy aging and dietary restriction life extension

▲ 27

Aging 2024

Open access · CC-BY

The coupling between healthspan and lifespan in Caenorhabditis depends on complex interactions between compound intervention and genetic background

▲ 21

Food & Function 2020

Citation only

Healthy lifespan extension mediated by oenothein B isolated from Eucalyptus grandis × Eucalyptus urophylla GL9 in Caenorhabditis elegans

▲ 18

GeroScience 2023

Open access · CC-BY

Antioxidants green tea extract and nordihydroguaiaretic acid confer species and strain-specific lifespan and health effects in Caenorhabditis nematodes

▲ 15

GeroScience 2025

Open access · CC0

NIA Caenorhabditis Intervention Testing Program: identification of robust and reproducible pharmacological interventions that promote longevity across experimentally accessible, genetically diverse populations

▲ 11

bioRxiv (Cold Spring Harbor Laboratory) 2022

Preprint · CC-BY

The coupling between healthspan and lifespan in Caenorhabditis depends on complex interactions between compound intervention and genetic background

▲ 3

eLife 2024

Preprint · CC-BY

Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically diverse Caenorhabditis nematodes

▲ 1

eLife 2025

Open access · CC-BY

Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically diverse Caenorhabditis nematodes

▲ 1

bioRxiv (Cold Spring Harbor Laboratory) 2021

Preprint · CC-BY

Antioxidants green tea extract and nordihydroguaiaretic acid confer species and strain specific lifespan and health effects in Caenorhabditis nematodes

▲ 1

Innovation in Aging 2022

Open access · CC-BY

ANTI-AGING COMPOUNDS METFORMIN AND THIOFLAVIN T CAN ACT ON GENETICALLY DIVERSE, PROTEOSTASIS-COMPROMISED STRAINS

▲ 0

PubMed Central 2026

Preprint · CC-BY

Caenorhabditis Intervention Testing Program: the putative mTOR inhibitors Cinnarizine and Meclizine do not extend lifespan in C. elegans

▲ 0

Collaborators

Works in the record

A Role for Autophagy in the Extension of Lifespan by Dietary Restriction in C. elegans

Metformin Induces a Dietary Restriction–Like State and the Oxidative Stress Response to Extend C. elegans Healthspan via AMPK, LKB1, and SKN-1

Impact of genetic background and experimental reproducibility on identifying chemical compounds with robust longevity effects

Deletion of microRNA-80 Activates Dietary Restriction to Extend C. elegans Healthspan and Lifespan

Mechanism of Longevity Extension of<i>Caenorhabditis elegans</i>Induced by Pentagalloyl Glucose Isolated from Eucalyptus Leaves

Metformin treatment of diverse Caenorhabditis species reveals the importance of genetic background in longevity and healthspan extension outcomes

Gluconeogenesis and PEPCK are critical components of healthy aging and dietary restriction life extension

The coupling between healthspan and lifespan in Caenorhabditis depends on complex interactions between compound intervention and genetic background

Healthy lifespan extension mediated by oenothein B isolated from Eucalyptus grandis × Eucalyptus urophylla GL9 in Caenorhabditis elegans

Antioxidants green tea extract and nordihydroguaiaretic acid confer species and strain-specific lifespan and health effects in Caenorhabditis nematodes

NIA Caenorhabditis Intervention Testing Program: identification of robust and reproducible pharmacological interventions that promote longevity across experimentally accessible, genetically diverse populations

The coupling between healthspan and lifespan in Caenorhabditis depends on complex interactions between compound intervention and genetic background

Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically diverse Caenorhabditis nematodes

Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically diverse Caenorhabditis nematodes

Antioxidants green tea extract and nordihydroguaiaretic acid confer species and strain specific lifespan and health effects in Caenorhabditis nematodes

ANTI-AGING COMPOUNDS METFORMIN AND THIOFLAVIN T CAN ACT ON GENETICALLY DIVERSE, PROTEOSTASIS-COMPROMISED STRAINS

Caenorhabditis Intervention Testing Program: the putative mTOR inhibitors Cinnarizine and Meclizine do not extend lifespan in C. elegans