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Tumor Microsatellite-Instability Status as a Predictor of Benefit from Fluorouracil-Based Adjuvant Chemotherapy for Colon Cancer

Christine Ribic, Daniel J. Sargent, Malcolm J. Moore, Stephen N. Thibodeau, Amy J. French, Richard M. Goldberg, Stanley R. Hamilton, Pierre Laurent‐Puig, Robert Gryfe, Lois E. Shepherd, Dongsheng Tu, Mark Redston, Steven Gallinger

New England Journal of Medicine · 2003 · ▲ 2,150 citations

Abstract

Colon cancers with high-frequency microsatellite instability have clinical and pathological features that distinguish them from microsatellite-stable tumors. We investigated the usefulness of microsatellite-instability status as a predictor of the benefit of adjuvant chemotherapy with fluorouracil in stage II and stage III colon cancer.

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OpenAlex
DOI
10.1056/nejmoa022289
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2026-06-02 MST

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APA
Ribic, C., Sargent, D.J., Moore, M.J., Thibodeau, S.N., French, A.J., Goldberg, R.M., Hamilton, S.R., Laurent‐Puig, P., Gryfe, R., Shepherd, L.E., Tu, D., Redston, M., &amp; Gallinger, S. (2003). Tumor Microsatellite-Instability Status as a Predictor of Benefit from Fluorouracil-Based Adjuvant Chemotherapy for Colon Cancer. <em>New England Journal of Medicine</em>. https://doi.org/10.1056/nejmoa022289
Vancouver
Ribic C, Sargent DJ, Moore MJ, Thibodeau SN, French AJ, Goldberg RM, et al. Tumor Microsatellite-Instability Status as a Predictor of Benefit from Fluorouracil-Based Adjuvant Chemotherapy for Colon Cancer. New England Journal of Medicine. 2003. doi:10.1056/nejmoa022289.
BibTeX
@article{christine2003TumorM, title = {Tumor Microsatellite-Instability Status as a Predictor of Benefit from Fluorouracil-Based Adjuvant Chemotherapy for Colon Cancer}, author = {Christine Ribic and Daniel J. Sargent and Malcolm J. Moore and Stephen N. Thibodeau and Amy J. French and Richard M. Goldberg and Stanley R. Hamilton and Pierre Laurent‐Puig and Robert Gryfe and Lois E. Shepherd and Dongsheng Tu and Mark Redston and Steven Gallinger}, journal = {New England Journal of Medicine}, year = {2003}, doi = {10.1056/nejmoa022289}, }

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