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Mitochondrial energy metabolism in heart failure: a question of balance

Journal of Clinical Investigation · 2005 · ▲ 519 citations

Mitochondrial dysfunction Altered intercellular communication Review

Abstract

The mitochondrion serves a critical role as a platform for energy transduction, signaling, and cell death pathways relevant to common diseases of the myocardium such as heart failure. This review focuses on the molecular regulatory events and downstream effector pathways involved in mitochondrial energy metabolic derangements known to occur during the development of heart failure.

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Provenance

Source: OpenAlex
DOI: 10.1172/jci24405
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Fetched: 2026-06-10 MST

Cite this

APA

Huss, J.M., & Kelly, D.P. (2005). Mitochondrial energy metabolism in heart failure: a question of balance. <em>Journal of Clinical Investigation</em>. https://doi.org/10.1172/jci24405

Vancouver

Huss JM, Kelly DP. Mitochondrial energy metabolism in heart failure: a question of balance. Journal of Clinical Investigation. 2005. doi:10.1172/jci24405.

BibTeX

@unpublished{janice2005Mitoch, title = {Mitochondrial energy metabolism in heart failure: a question of balance}, author = {Janice M. Huss and Daniel P. Kelly}, journal = {Journal of Clinical Investigation}, year = {2005}, doi = {10.1172/jci24405}, }