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Interference between PARPs and SIRT1: a novel approach to healthy ageing?

Aging · 2011 · ▲ 50 citations

Genomic instability

Abstract

Poly(ADP-ribosyl) polymerases (PARPs) have traditionally been linked to chromosome maintenance and DNA repair. Recent findings identify PARPs as key modulators of metabolism through their influence on SIRT1 activity, hinting to a possible role of PARPs as longevity regulators.

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Provenance

Source: OpenAlex
DOI: 10.18632/aging.100326
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Fetched: 2026-10-23 MST

Cite this

APA

Cantó, C., & Auwerx, J.H. (2011). Interference between PARPs and SIRT1: a novel approach to healthy ageing?. <em>Aging</em>. https://doi.org/10.18632/aging.100326

Vancouver

Cantó C, Auwerx JH. Interference between PARPs and SIRT1: a novel approach to healthy ageing?. Aging. 2011. doi:10.18632/aging.100326.

BibTeX

@article{carles2011Interf, title = {Interference between PARPs and SIRT1: a novel approach to healthy ageing?}, author = {Carles Cantó and Johan H. Auwerx}, journal = {Aging}, year = {2011}, doi = {10.18632/aging.100326}, }