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Energizing Mitochondria to Prevent Mobility Loss in Aging: Rationale and Hypotheses

Qu Tian, Philip R. Lee, Keenan A. Walker, Luigi Ferrucci

Exercise and Sport Sciences Reviews · 2023 · ▲ 19 citations

Mitochondrial dysfunction Partial reprogramming (OSK)

Abstract

Based on recent studies from our group and others, we hypothesize that mitochondrial dysfunction during aging may be the root cause of mobility decline through deficits in the musculoskeletal and central nervous systems. Mitochondrial dysfunction could be a therapeutic target to prevent mobility decline in aging.

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Provenance

Source: OpenAlex
DOI: 10.1249/jes.0000000000000315
Canonical: link ↗
Fetched: 2026-07-08 MST

Cite this

APA

Tian, Q., Lee, P.R., Walker, K.A., & Ferrucci, L. (2023). Energizing Mitochondria to Prevent Mobility Loss in Aging: Rationale and Hypotheses. <em>Exercise and Sport Sciences Reviews</em>. https://doi.org/10.1249/jes.0000000000000315

Vancouver

Tian Q, Lee PR, Walker KA, Ferrucci L. Energizing Mitochondria to Prevent Mobility Loss in Aging: Rationale and Hypotheses. Exercise and Sport Sciences Reviews. 2023. doi:10.1249/jes.0000000000000315.

BibTeX

@unpublished{qu2023Energi, title = {Energizing Mitochondria to Prevent Mobility Loss in Aging: Rationale and Hypotheses}, author = {Qu Tian and Philip R. Lee and Keenan A. Walker and Luigi Ferrucci}, journal = {Exercise and Sport Sciences Reviews}, year = {2023}, doi = {10.1249/jes.0000000000000315}, }