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DNA methylation-based measures of biological age: meta-analysis predicting time to death

Brian H. Chen, Riccardo E. Marioni, Elena Colicino, Marjolein J. Peters, Cavin Ward‐Caviness, Pei-Chien Tsai, Nicholas S. Roetker, Allan C. Just, Ellen W. Demerath, Weihua Guan, Jan Bressler, Myriam Fornage, Stephanie A. Studenski, Amy R. Vandiver, Ann Zenobia Moore

Aging · 2016 · ▲ 1,215 citations

Epigenetic alterations Meta-analysis

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Abstract

). Overall, this study a) strengthens the evidence that epigenetic age predicts all-cause mortality above and beyond chronological age and traditional risk factors, and b) demonstrates that epigenetic age estimates that incorporate information on blood cell counts lead to highly significant associations with all-cause mortality.

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Provenance

Source: OpenAlex
DOI: 10.18632/aging.101020
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Fetched: 2026-06-12 MST

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APA

Chen, B.H., Marioni, R.E., Colicino, E., Peters, M.J., Ward‐Caviness, C., Tsai, P., Roetker, N.S., Just, A.C., Demerath, E.W., Guan, W., Bressler, J., Fornage, M., Studenski, S.A., Vandiver, A.R., Moore, A.Z., Tanaka, T., Kiel, D.P., Liang, L., Vokonas, P., & Schwartz, J. (2016). DNA methylation-based measures of biological age: meta-analysis predicting time to death. <em>Aging</em>. https://doi.org/10.18632/aging.101020

Vancouver

Chen BH, Marioni RE, Colicino E, Peters MJ, Ward‐Caviness C, Tsai P, et al. DNA methylation-based measures of biological age: meta-analysis predicting time to death. Aging. 2016. doi:10.18632/aging.101020.

BibTeX

@unpublished{brian2016DNAmet, title = {DNA methylation-based measures of biological age: meta-analysis predicting time to death}, author = {Brian H. Chen and Riccardo E. Marioni and Elena Colicino and Marjolein J. Peters and Cavin Ward‐Caviness and Pei-Chien Tsai and Nicholas S. Roetker and Allan C. Just and Ellen W. Demerath and Weihua Guan and Jan Bressler and Myriam Fornage and Stephanie A. Studenski and Amy R. Vandiver and Ann Zenobia Moore and Toshiko Tanaka and Douglas P. Kiel and Liming Liang and Pantel Vokonas and Joel Schwartz and Kathryn L. Lunetta and Joanne M. Murabito and Stefania Bandinelli and Dena Hernández and David Melzer}, journal = {Aging}, year = {2016}, doi = {10.18632/aging.101020}, }