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Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel

Hartmut Döhner, Elihu H. Estey, David Grimwade, Sergio Amadori, Frederick R. Appelbaum, Thomas Büchner, Hervé Dombret, Benjamin L. Ebert, Pierre Fenaux, Richard A. Larson, Ross L. Levine, Francesco Lo‐Coco, Tomoki Naoe, Dietger Niederwieser, Gert J. Ossenkoppele

Blood · 2016 · ▲ 5,854 citations

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Abstract

The first edition of the European LeukemiaNet (ELN) recommendations for diagnosis and management of acute myeloid leukemia (AML) in adults, published in 2010, has found broad acceptance by physicians and investigators caring for patients with AML. Recent advances, for example, in the discovery of the genomic landscape of the disease, in the development of assays for genetic testing and for detecting minimal residual disease (MRD), as well as in the development of novel antileukemic agents, prompted an international panel to provide updated evidence- and expert opinion-based recommendations. The recommendations include a revised version of the ELN genetic categories, a proposal for a response category based on MRD status, and criteria for progressive disease.

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Provenance

Source: OpenAlex
DOI: 10.1182/blood-2016-08-733196
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Fetched: 2026-06-05 MST

Cite this

APA

Döhner, H., Estey, E.H., Grimwade, D., Amadori, S., Appelbaum, F.R., Büchner, T., Dombret, H., Ebert, B.L., Fenaux, P., Larson, R.A., Levine, R.L., Lo‐Coco, F., Naoe, T., Niederwieser, D., Ossenkoppele, G.J., Sanz, M.�., Sierra, J., Tallman, M.S., Tien, H., & Wei, A.H. (2016). Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel. <em>Blood</em>. https://doi.org/10.1182/blood-2016-08-733196

Vancouver

Döhner H, Estey EH, Grimwade D, Amadori S, Appelbaum FR, Büchner T, et al. Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel. Blood. 2016. doi:10.1182/blood-2016-08-733196.

BibTeX

@article{hartmut2016Diagno, title = {Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel}, author = {Hartmut Döhner and Elihu H. Estey and David Grimwade and Sergio Amadori and Frederick R. Appelbaum and Thomas Büchner and Hervé Dombret and Benjamin L. Ebert and Pierre Fenaux and Richard A. Larson and Ross L. Levine and Francesco Lo‐Coco and Tomoki Naoe and Dietger Niederwieser and Gert J. Ossenkoppele and Miguel Á. Sanz and Jorge Sierra and Martin S. Tallman and Hwei‐Fang Tien and Andrew H. Wei and Bob Löwenberg and Clara D. Bloomfield}, journal = {Blood}, year = {2016}, doi = {10.1182/blood-2016-08-733196}, }