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Ancient DNA Damage

Cold Spring Harbor Perspectives in Biology · 2013 · ▲ 521 citations

Genomic instability

Abstract

Under favorable conditions DNA can survive for thousands of years in the remains of dead organisms. The DNA extracted from such remains is invariably degraded to a small average size by processes that at least partly involve depurination. It also contains large amounts of deaminated cytosine residues that are accumulated toward the ends of the molecules, as well as several other lesions that are less well characterized.

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Provenance

Source: OpenAlex
DOI: 10.1101/cshperspect.a012567
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Fetched: 2026-06-12 MST

Cite this

APA

Dabney, J., Meyer, M., & Paabo, S. (2013). Ancient DNA Damage. <em>Cold Spring Harbor Perspectives in Biology</em>. https://doi.org/10.1101/cshperspect.a012567

Vancouver

Dabney J, Meyer M, Paabo S. Ancient DNA Damage. Cold Spring Harbor Perspectives in Biology. 2013. doi:10.1101/cshperspect.a012567.

BibTeX

@article{jesse2013Ancien, title = {Ancient DNA Damage}, author = {Jesse Dabney and Matthias Meyer and S. Paabo}, journal = {Cold Spring Harbor Perspectives in Biology}, year = {2013}, doi = {10.1101/cshperspect.a012567}, }