Willard M. Freeman

Pharmacology & Therapeutics · 2018

⊕ Open access · CC-BY

The role of DNA methylation in epigenetics of aging

▲ 399

Nature Aging · 2024

⊕ Open access · CC-BY

A single-cell atlas of the aging mouse ovary

▲ 178

Journal of Neuroinflammation · 2011

⊕ Open access · CC-BY

Concurrent hippocampal induction of MHC II pathway components and glial activation with advanced aging is not correlated with cognitive impairment

▲ 138

Frontiers in Aging Neuroscience · 2013

⊕ Open access · CC-BY

Insulin-like growth factor-1 in CNS and cerebrovascular aging

▲ 137

Aging Cell · 2021

⊕ Open access · CC-BY

Many chronological aging clocks can be found throughout the epigenome: Implications for quantifying biological aging

▲ 71

Neurobiology of Aging · 2018

◌ Citation only

Caloric restriction mitigates age-associated hippocampal differential CG and non-CG methylation

▲ 66

Aging Cell · 2017

⊕ Open access · CC-BY

17α‐estradiol acts through hypothalamic pro‐opiomelanocortin expressing neurons to reduce feeding behavior

▲ 55

The Journals of Gerontology Series A · 2015

⊕ Open access · OA

Recent Developments in Understanding Brain Aging: Implications for Alzheimer’s Disease and Vascular Cognitive Impairment

▲ 43

Epigenetics & Chromatin · 2019

⊕ Open access · CC-BY

Early-life DNA methylation profiles are indicative of age-related transcriptome changes

▲ 35

GeroScience · 2023

⊕ Preprint · OA

Assessing tolerability and physiological responses to 17α-estradiol administration in male rhesus macaques

▲ 11

bioRxiv (Cold Spring Harbor Laboratory) · 2020

⊕ Preprint · CC-BY

Health benefits attributed to 17α-estradiol, a lifespan-extending compound, are mediated through estrogen receptor α

▲ 2

bioRxiv (Cold Spring Harbor Laboratory) · 2022

⊕ Preprint · CC-BY

17α-estradiol, a lifespan-extending compound, attenuates liver fibrosis by modulating collagen turnover rates in male mice

▲ 1