Stephan J. Sigrist

Nature Neuroscience · 2013

⊕ Preprint · OA

Restoring polyamines protects from age-induced memory impairment in an autophagy-dependent manner

▲ 375

PLoS Biology · 2016

⊕ Open access · CC-BY

Spermidine Suppresses Age-Associated Memory Impairment by Preventing Adverse Increase of Presynaptic Active Zone Size and Release

▲ 112

Journal of Neuroinflammation · 2022

⊕ Open access · CC-BY

Spermidine reduces neuroinflammation and soluble amyloid beta in an Alzheimer’s disease mouse model

▲ 105

Cell Death and Disease · 2012

⊕ Open access · CC-BY

Spermidine promotes stress resistance in Drosophila melanogaster through autophagy-dependent and -independent pathways

▲ 104

Alzheimer s Research & Therapy · 2019

⊕ Open access · CC-BY

Effects of spermidine supplementation on cognition and biomarkers in older adults with subjective cognitive decline (SmartAge)—study protocol for a randomized controlled trial

▲ 100

JAMA Network Open · 2022

⊕ Open access · CC-BY

Effects of Spermidine Supplementation on Cognition and Biomarkers in Older Adults With Subjective Cognitive Decline

▲ 91

Autophagy · 2021

⊕ Open access · CC-BY

Spermidine-induced hypusination preserves mitochondrial and cognitive function during aging

▲ 83

Scientific Reports · 2019

⊕ Open access · CC-BY

Spermidine protects from age-related synaptic alterations at hippocampal mossy fiber-CA3 synapses

▲ 56

GeroScience · 2021

⊕ Open access · CC-BY

Novel aspects of age-protection by spermidine supplementation are associated with preserved telomere length

▲ 40

Neuron · 2025

⊕ Open access · CC-BY

Neuronal autophagy in the control of synapse function

▲ 32