Michele Vendruscolo

Molecular Psychiatry · 2021

⊕ Open access · CC-BY

The Amyloid-β Pathway in Alzheimer’s Disease

▲ 1,778

Cell · 2011

⊕ Open access · OA

Amyloid-like Aggregates Sequester Numerous Metastable Proteins with Essential Cellular Functions

▲ 718

Cell Reports · 2013

⊕ Open access · CC-BY

Widespread Aggregation and Neurodegenerative Diseases Are Associated with Supersaturated Proteins

▲ 270

Molecular Systems Biology · 2020

⊕ Open access · CC-BY

Reduced proteasome activity in the aging brain results in ribosome stoichiometry loss and aggregation

▲ 235

Nature Communications · 2022

⊕ Open access · CC-BY

Small soluble α-synuclein aggregates are the toxic species in Parkinson’s disease

▲ 222

Proceedings of the National Academy of Sciences · 2019

⊕ Open access · OA

Proteome-wide observation of the phenomenon of life on the edge of solubility

▲ 169

Cold Spring Harbor Perspectives in Biology · 2011

⊕ Preprint · OA

Protein Solubility and Protein Homeostasis: A Generic View of Protein Misfolding Disorders

▲ 109

Aging · 2020

⊕ Preprint · CC-BY

Cholesterol-rich naked mole-rat brain lipid membranes are susceptible to amyloid beta-induced damage in vitro

▲ 20

bioRxiv (Cold Spring Harbor Laboratory) · 2019

⊕ Preprint · CC-BY

Reduced proteasome activity in the aging brain results in ribosome stoichiometry loss and aggregation

▲ 15

PLoS Computational Biology · 2025

⊕ Open access · CC-BY

Proteostasis signatures in human diseases

▲ 11

bioRxiv (Cold Spring Harbor Laboratory) · 2020

⊕ Preprint · CC-BY

Lipid membranes from naked mole-rat brain lipids are cholesterol-rich, highly phase-separated, and sensitive to amyloid-induced damage

▲ 0