Author
Michael B. Stout
- Indexed works
- 33
- Total citations
- 7,092
- Active years
- 10
Collaborators
Works in the record
Aging Cell 2015
Open access · CC-BY
The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs
Aging Cell 2015
Open access · CC-BY
Identification of a novel senolytic agent, navitoclax, targeting the Bcl‐2 family of anti‐apoptotic factors
Proceedings of the National Academy of Sciences 2015
Open access · OA
JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age
Aging Cell 2019
Open access · CC-BY
Targeting senescent cells alleviates obesity‐induced metabolic dysfunction
eLife 2015
Open access · CC-BY
Targeting senescent cells enhances adipogenesis and metabolic function in old age
Physiology 2016
Preprint · OA
Physiological Aging: Links Among Adipose Tissue Dysfunction, Diabetes, and Frailty
Diabetes 2016
Preprint · OA
Exercise Prevents Diet-Induced Cellular Senescence in Adipose Tissue
Nature Aging 2024
Open access · CC-BY
A single-cell atlas of the aging mouse ovary
The Journals of Gerontology Series A 2016
Open access · CC-BY
17α-Estradiol Alleviates Age-related Metabolic and Inflammatory Dysfunction in Male Mice Without Inducing Feminization
npj Aging 2024
Open access · CC-BY
The role of cellular senescence in ovarian aging
The Journals of Gerontology Series A 2016
Open access · CC-BY
Evaluating Health Span in Preclinical Models of Aging and Disease: Guidelines, Challenges, and Opportunities for Geroscience
Aging Cell 2017
Open access · CC-BY
17α‐estradiol acts through hypothalamic pro‐opiomelanocortin expressing neurons to reduce feeding behavior
Experimental Gerontology 2020
Open access · CC-BY
17α-Estradiol prevents ovariectomy-mediated obesity and bone loss
GeroScience 2022
Preprint · OA
Senolytic treatment reverses obesity-mediated senescent cell accumulation in the ovary
GeroScience 2024
Preprint · OA
Senolytic treatment fails to improve ovarian reserve or fertility in female mice
Scientific Reports 2023
Open access · CC-BY
Metabolic benefits of 17α-estradiol in liver are partially mediated by ERβ in male mice
GeroScience 2022
Preprint · OA
17α-estradiol does not adversely affect sperm parameters or fertility in male mice: implications for reproduction-longevity trade-offs
The Journals of Gerontology Series A 2023
Open access · CC-BY
A Genetically Heterogeneous Rat Model with Divergent Mitochondrial Genomes
Physiology International 2023
Open access · OA
Dasatinib and quercetin increase testosterone and sperm concentration in mice
Aging 2018
Open access · OA
Hormone actions controlling sex-specific life-extension
GeroScience 2024
Preprint · OA
Canagliflozin treatment prevents follicular exhaustion and attenuates hallmarks of ovarian aging in genetically heterogenous mice
Scientific Reports 2024
Open access · CC-BY
MASLD does not affect fertility and senolytics fail to prevent MASLD progression in male mice
GeroScience 2023
Preprint · OA
Assessing tolerability and physiological responses to 17α-estradiol administration in male rhesus macaques
GeroScience 2024
Open access · CC-BY
Systemic metabolic benefits of 17α-estradiol are not exclusively mediated by ERα in glutamatergic or GABAergic neurons
Aging Cell 2024
Open access · CC-BY
Metformin treatment results in distinctive skeletal muscle mitochondrial remodeling in rats with different intrinsic aerobic capacities
Biology of Reproduction 2026
Citation only
Reduced fertility induced by MASLD in female mice is improved by senolytic treatment
GeroScience 2024
Preprint · OA
A pilot study evaluating dosing tolerability of 17α-estradiol in male common marmosets (Callithrix jacchus)
PLoS ONE 2024
Open access · CC-BY
Negative effects of lifespan extending intervention on resilience in mice
bioRxiv (Cold Spring Harbor Laboratory) 2020
Preprint · CC-BY
Health benefits attributed to 17α-estradiol, a lifespan-extending compound, are mediated through estrogen receptor α
bioRxiv (Cold Spring Harbor Laboratory) 2022
Preprint · CC-BY
17α-estradiol, a lifespan-extending compound, attenuates liver fibrosis by modulating collagen turnover rates in male mice
Research Square 2026
Preprint · CC-BY
Multimodal profiling establishes ovarian fibrosis as a measurable and targetable hallmark of human reproductive aging
Ageing Research Reviews 2026
Preprint · OA
17α-Estradiol: A mildly feminizing estrogen with sex-specific metabolic and lifespan benefits
bioRxiv (Cold Spring Harbor Laboratory) 2024
Preprint · OA