John M. Sedivy

Cell · 2019

⊕ Open access · OA

Cellular Senescence: Defining a Path Forward

▲ 3,178

Molecular Cell · 2004

⊕ Open access · OA

Telomere Shortening Triggers Senescence of Human Cells through a Pathway Involving ATM, p53, and p21CIP1, but Not p16INK4a

▲ 1,290

Nature · 2019

◌ Citation only

L1 drives IFN in senescent cells and promotes age-associated inflammation

▲ 1,234

Science · 2006

◌ Citation only

Cellular Senescence in Aging Primates

▲ 1,080

Aging Cell · 2015

⊕ Open access · CC-BY

Interventions to Slow Aging in Humans: Are We Ready?

▲ 607

Signal Transduction and Targeted Therapy · 2021

⊕ Open access · CC-BY

Inflammation, epigenetics, and metabolism converge to cell senescence and ageing: the regulation and intervention

▲ 396

Mechanisms of Ageing and Development · 2008

⊕ Preprint · OA

Cellular senescence and organismal aging

▲ 342

Cell · 2015

⊕ Open access · OA

Reduced Expression of MYC Increases Longevity and Enhances Healthspan

▲ 311

Cell Reports · 2018

⊕ Open access · CC-BY

Regulation of Cellular Senescence by Polycomb Chromatin Modifiers through Distinct DNA Damage- and Histone Methylation-Dependent Pathways

▲ 263

Journal of Biological Chemistry · 2003

⊕ Open access · CC-BY

Telomerase Expression in Normal Human Fibroblasts Stabilizes DNA 5-Methylcytosine Transferase I

▲ 66

Biophysical Journal · 2021

⊕ Open access · OA

Phase separation of the LINE-1 ORF1 protein is mediated by the N-terminus and coiled-coil domain

▲ 56

Proceedings of the National Academy of Sciences · 2022

⊕ Open access · CC-BY

Sirt6 regulates lifespan in <i>Drosophila melanogaster</i>

▲ 52

PLoS ONE · 2010

⊕ Open access · CC-BY

Regulation of Gene Expression in Hepatic Cells by the Mammalian Target of Rapamycin (mTOR)

▲ 28

Signal Transduction and Targeted Therapy · 2020

⊕ Open access · CC-BY

L1 drives HSC aging and affects prognosis of chronic myelomonocytic leukemia

▲ 4