David Vı́lchez

Nature Communications · 2014

⊕ Open access · OA

The role of protein clearance mechanisms in organismal ageing and age-related diseases

▲ 684

Nature · 2012

◌ Citation only

RPN-6 determines C. elegans longevity under proteotoxic stress conditions

▲ 416

Nature · 2012

⊕ Preprint · OA

Increased proteasome activity in human embryonic stem cells is regulated by PSMD11

▲ 410

Nature Communications · 2019

⊕ Open access · CC-BY

The autophagy receptor p62/SQST-1 promotes proteostasis and longevity in C. elegans by inducing autophagy

▲ 144

Nature Communications · 2018

⊕ Open access · CC-BY

The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington’s disease patients

▲ 109

Nature Communications · 2016

⊕ Open access · CC-BY

Somatic increase of CCT8 mimics proteostasis of human pluripotent stem cells and extends C. elegans lifespan

▲ 89

International Journal of Molecular Sciences · 2017

⊕ Open access · CC-BY

Proteostasis of Huntingtin in Health and Disease

▲ 59

Frontiers in Aging · 2022

⊕ Open access · CC-BY

Insights Into the Links Between Proteostasis and Aging From C. elegans

▲ 32

Frontiers in Molecular Biosciences · 2015

⊕ Open access · CC-BY

Mediation of organismal aging and somatic proteostasis by the germline

▲ 27

Neural Regeneration Research · 2019

⊕ Open access · CC-BY

Induced pluripotent stem cells from Huntington’s disease patients: a promising approach to define and correct disease-related alterations

▲ 10

Nature Aging · 2025

⊕ Open access · CC-BY

The aging factor EPS8 induces disease-related protein aggregation through RAC signaling hyperactivation

▲ 9

AIMS molecular science · 2015

⊕ Open access · CC-BY

Protein clearance mechanisms and their demise in age-related neurodegenerative diseases

▲ 2