David Sinclair

Aging · 2020

⊕ Open access · CC-BY

Why does COVID-19 disproportionately affect older people?

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Cell Metabolism · 2014

⊕ Open access · OA

The Ratio of Macronutrients, Not Caloric Intake, Dictates Cardiometabolic Health, Aging, and Longevity in Ad Libitum-Fed Mice

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Cell Metabolism · 2018

⊕ Open access · OA

Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice

▲ 331

Nature Aging · 2021

⊕ Open access · CC-BY

The economic value of targeting aging

▲ 285

Aging · 2009

⊕ Open access · CC-BY

Inhibition of mammalian S6 kinase by resveratrol suppresses autophagy

▲ 159

Proceedings of the National Academy of Sciences · 1999

⊕ Open access · OA

Passage through stationary phase advances replicative aging in Saccharomyces cerevisiae

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Nature Communications · 2020

⊕ Open access · CC-BY

Age and life expectancy clocks based on machine learning analysis of mouse frailty

▲ 137

Aging · 2023

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Chemically induced reprogramming to reverse cellular aging

▲ 134

Frontiers in Pharmacology · 2016

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Head to Head Comparison of Short-Term Treatment with the NAD+ Precursor Nicotinamide Mononucleotide (NMN) and 6 Weeks of Exercise in Obese Female Mice

▲ 95

Aging Cell · 2014

⊕ Open access · CC-BY

Dietary restriction involves NAD +‐dependent mechanisms and a shift toward oxidative metabolism

▲ 91

Mechanisms of Ageing and Development · 2016

⊕ Preprint · OA

C. elegans lifespan extension by osmotic stress requires FUdR, base excision repair, FOXO, and sirtuins

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Scientific Reports · 2017

⊕ Open access · CC-BY

Nicotinamide mononucleotide (NMN) supplementation ameliorates the impact of maternal obesity in mice: comparison with exercise

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Aging · 2020

⊕ Open access · CC-BY

Biomarkers of biological age as predictors of COVID-19 disease severity

▲ 63

Nature Aging · 2023

⊕ Preprint · OA

Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming

▲ 58

Molecular Metabolism · 2017

⊕ Open access · CC-BY

Skeletal muscle overexpression of nicotinamide phosphoribosyl transferase in mice coupled with voluntary exercise augments exercise endurance

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The Journal of Clinical Endocrinology & Metabolism · 2023

⊕ Open access · OA

Nicotinamide Adenine Dinucleotide Augmentation in Overweight or Obese Middle-Aged and Older Adults: A Physiologic Study

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Aging Cell · 2009

⊕ Open access · OA

NQR1 controls lifespan by regulating the promotion of respiratory metabolism in yeast

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Reproduction · 2019

⊕ Open access · CC-BY

Impacts of obesity, maternal obesity and nicotinamide mononucleotide supplementation on sperm quality in mice

▲ 39

Cells · 2020

⊕ Open access · CC-BY

Administration of Nicotinamide Mononucleotide (NMN) Reduces Metabolic Impairment in Male Mouse Offspring from Obese Mothers

▲ 33

Cellular Reprogramming · 2023

⊕ Preprint · OA

Sustained Vision Recovery by OSK Gene Therapy in a Mouse Model of Glaucoma

▲ 33

FEBS Letters · 2023

⊕ Open access · OA

Host–microbiome interactions in nicotinamide mononucleotide (NMN) deamidation

▲ 29

bioRxiv (Cold Spring Harbor Laboratory) · 2019

⊕ Preprint · CC-BY

Age and life expectancy clocks based on machine learning analysis of mouse frailty

▲ 29

bioRxiv (Cold Spring Harbor Laboratory) · 2020

⊕ Preprint · CC-BY

Nicotinamide mononucleotide (NMN) deamidation by host-microbiome interactions

▲ 14

2020

⊕ Preprint · CC-BY

Nicotinamide mononucleotide (NMN) deamidation and indirect regulation of the NAD metabolome

▲ 1