David M. Sabatini

Nature · 2010

◌ Citation only

mTORC1 controls fasting-induced ketogenesis and its modulation by ageing

▲ 657

Journal of Clinical Investigation · 2013

⊕ Open access · OA

Rapalogs and mTOR inhibitors as anti-aging therapeutics

▲ 544

Nature · 2012

⊕ Preprint · CC-BY

Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival

▲ 460

Trends in Molecular Medicine · 2012

⊕ Open access · OA

Amino acids and mTORC1: from lysosomes to disease

▲ 440

Aging Cell · 2016

⊕ Open access · CC-BY

Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α‐glucosidase inhibitor or a Nrf2‐inducer

▲ 381

Journal of Cell Science · 2019

⊕ Open access · OA

Nutrient regulation of mTORC1 at a glance

▲ 333

Science Advances · 2020

⊕ Open access · CC-BY

MCART1/SLC25A51 is required for mitochondrial NAD transport

▲ 202

Aging Cell · 2014

⊕ Open access · CC-BY

Depletion of Rictor, an essential protein component of m<scp>TORC</scp>2, decreases male lifespan

▲ 115

Frontiers in Genetics · 2012

⊕ Open access · CC-BY

Rapamycin has a biphasic effect on insulin sensitivity in C2C12 myotubes due to sequential disruption of mTORC1 and mTORC2

▲ 81

Science · 2012

⊕ Preprint · OA

Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity

▲ 69

eLife · 2024

⊕ Open access · CC-BY

Organelle proteomic profiling reveals lysosomal heterogeneity in association with longevity

▲ 36

PubMed · 2014

⊕ Preprint · CC-BY

Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan.

▲ 10