Author
David Gems
- Indexed works
- 40
- Total citations
- 5,255
- Active years
- 19
Collaborators
Works in the record
Nature Metabolism 2022
Open access · OA
Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo
Cell 2013
Open access · CC-BY
Metformin Retards Aging in C. elegans by Altering Microbial Folate and Methionine Metabolism
Aging Cell 2015
Open access · CC-BY
Interventions to Slow Aging in Humans: Are We Ready?
The FASEB Journal 2007
Citation only
Evidence for lifespan extension and delayed age–related biomarkers in insulin receptor substrate 1 null mice
Aging Cell 2017
Open access · CC-BY
The SKN ‐1/Nrf2 transcription factor can protect against oxidative stress and increase lifespan in C. elegans by distinct mechanisms
BMC Biology 2006
Open access · CC-BY
Long-term starvation and ageing induce AGE-1/PI 3-kinase-dependent translocation of DAF-16/FOXO to the cytoplasm
Experimental Gerontology 2004
Citation only
Metabolic rate is not reduced by dietary-restriction or by lowered insulin/IGF-1 signalling and is not correlated with individual lifespan in Drosophila melanogaster
Free Radical Biology and Medicine 2011
Open access · CC-BY
Increased life span from overexpression of superoxide dismutase in Caenorhabditis elegans is not caused by decreased oxidative damage
Molecular Systems Biology 2010
Open access · OA
DamID in C. elegans reveals longevity‐associated targets of DAF‐16/FoxO
Ageing Research Reviews 2021
Preprint · CC-BY
The hoverfly and the wasp: A critique of the hallmarks of aging as a paradigm
PLoS Genetics 2007
Open access · CC-BY
No Influence of Indy on Lifespan in Drosophila after Correction for Genetic and Cytoplasmic Background Effects
Genetics 2008
Open access · OA
Clustering of Genetically Defined Allele Classes in the Caenorhabditis elegans DAF-2 Insulin/IGF-1 Receptor
PLoS Genetics 2014
Open access · CC-BY
DAF-16/FoxO Directly Regulates an Atypical AMP-Activated Protein Kinase Gamma Isoform to Mediate the Effects of Insulin/IGF-1 Signaling on Aging in Caenorhabditis elegans
PLoS Genetics 2012
Open access · CC-BY
Insulin/IGF-1 and Hypoxia Signaling Act in Concert to Regulate Iron Homeostasis in Caenorhabditis elegans
Cell Reports 2017
Open access · CC-BY
Nutritional Programming of Lifespan by FOXO Inhibition on Sugar-Rich Diets
Cell Reports 2014
Open access · CC-BY
Cell-Nonautonomous Effects of dFOXO/DAF-16 in Aging
Aging Cell 2005
Open access · OA
LET‐60 RAS modulates effects of insulin/IGF‐1 signaling on development and aging in Caenorhabditis elegans
Nature Communications 2019
Open access · CC-BY
A fln-2 mutation affects lethal pathology and lifespan in C. elegans
Ageing Research Reviews 2024
Open access · CC-BY
Epigenetic clocks and programmatic aging
GeroScience 2022
Open access · CC-BY
Is “cellular senescence” a misnomer?
GeroScience 2024
Open access · CC-BY
Improved resilience and proteostasis mediate longevity upon DAF-2 degradation in old age
EMBO Reports 2024
Open access · CC-BY
Inflated expectations: the strange craze for translational research on aging
The Journals of Gerontology Series A 2024
Open access · CC-BY
Characterization of Effects of mTOR Inhibitors on Aging in Caenorhabditis elegans
F1000 Biology Reports 2010
Open access · OA
Treating aging: progress toward dietary restriction mimetics
Preprints.org 2025
Preprint · CC-BY
Against “Extending Healthspan but Not Lifespan” as a Goal for Biogerontology
bioRxiv (Cold Spring Harbor Laboratory) 2025
Preprint · CC-BY
Effects of knockdown of autophagy pathway genes on C. elegans longevity are highly condition dependent
Preprints.org 2022
Preprint · CC-BY
Is “Cellular Senescence” a Misnomer?
2026
Open access · CC-BY
Author response: Effects of knockdown of autophagy pathway genes on C. elegans longevity are highly condition dependent
2026
Open access · CC-BY
Reviewer #2 (Public review): Effects of knockdown of autophagy pathway genes on C. elegans longevity are highly condition dependent
2026
Open access · CC-BY
Reviewer #2 (Public review): Effects of knockdown of autophagy pathway genes on C. elegans longevity are highly condition dependent
2026
Open access · CC-BY
Reviewer #1 (Public review): Effects of knockdown of autophagy pathway genes on C. elegans longevity are highly condition dependent
2026
Open access · CC-BY
Reviewer #1 (Public review): Effects of knockdown of autophagy pathway genes on C. elegans longevity are highly condition dependent
bioRxiv (Cold Spring Harbor Laboratory) 2026
Preprint · CC-BY
Strong inhibition of insulin/IGF-1 signaling in early-mid adulthood compresses morbidity, but in later life accelerates aging
UCL Discovery (University College London) 2012
Preprint
Insulin/IGF-1 and hypoxia signaling act in concert to regulate iron homeostasis in C. elegans
GeroScience 2026
Open access · CC-BY
Against the “extend healthspan but not lifespan” cliché
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature 2009
Preprint
Faculty Opinions recommendation of Rapamycin fed late in life extends lifespan in genetically heterogeneous mice.
eLife 2026
Preprint · CC-BY
Effects of knockdown of autophagy pathway genes on C. elegans longevity are highly condition dependent
eLife 2026
Preprint · CC-BY
Effects of knockdown of autophagy pathway genes on C. elegans longevity are highly condition dependent
eLife 2026
Preprint · CC-BY
Effects of knockdown of autophagy pathway genes on C. elegans longevity are highly condition dependent
eLife 2026
Preprint · CC-BY