Collin Y. Ewald

Nature · 2014

⊕ Preprint · OA

Dauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity

▲ 375

Nature Communications · 2022

⊕ Open access · CC-BY

ATF-4 and hydrogen sulfide signalling mediate longevity in response to inhibition of translation or mTORC1

▲ 106

Gerontology · 2019

⊕ Preprint · OA

The Matrisome during Aging and Longevity: A Systems-Level Approach toward Defining Matreotypes Promoting Healthy Aging

▲ 100

Aging and Disease · 2023

⊕ Open access · CC-BY

Extracellular Matrix Dynamics as an Emerging yet Understudied Hallmark of Aging and Longevity

▲ 99

Gerontology · 2017

⊕ Preprint · OA

Untangling Longevity, Dauer, and Healthspan in Caenorhabditis elegans Insulin/IGF-1-Signalling

▲ 70

eLife · 2021

⊕ Open access · CC-BY

End-of-life targeted degradation of DAF-2 insulin/IGF-1 receptor promotes longevity free from growth-related pathologies

▲ 65

Nutrients · 2023

⊕ Open access · CC-BY

Potential Synergistic Supplementation of NAD+ Promoting Compounds as a Strategy for Increasing Healthspan

▲ 58

Aging · 2020

⊕ Preprint · CC-BY

ARDD 2020: from aging mechanisms to interventions

▲ 57

Cell Systems · 2021

⊕ Preprint · OA

Multiomic profiling of the liver across diets and age in a diverse mouse population

▲ 54

Aging Cell · 2021

⊕ Open access · CC-BY

Youthful and age‐related matreotypes predict drugs promoting longevity

▲ 49

Nature Communications · 2024

⊕ Open access · CC-BY

Longevity interventions modulate mechanotransduction and extracellular matrix homeostasis in C. elegans

▲ 49

iScience · 2022

⊕ Open access · CC-BY

Longevity interventions temporally scale healthspan in Caenorhabditis elegans

▲ 39

Aging · 2018

⊕ Preprint · OA

Aging and drug discovery

▲ 35

Aging Cell · 2016

⊕ Open access · CC-BY

Alzheimer‐related protein APL ‐1 modulates lifespan through heterochronic gene regulation in Caenorhabditis elegans

▲ 32

Frontiers in Aging · 2022

⊕ Open access · CC-BY

Longevity-Promoting Pathways and Transcription Factors Respond to and Control Extracellular Matrix Dynamics During Aging and Disease

▲ 28

Trends in Pharmacological Sciences · 2024

⊕ Open access · CC-BY

TNIK’s emerging role in cancer, metabolism, and age-related diseases

▲ 27

Aging Cell · 2023

⊕ Open access · CC-BY

Rilmenidine extends lifespan and healthspan in Caenorhabditis elegans via a nischarin I1 ‐imidazoline receptor

▲ 24

Frontiers in Aging · 2023

⊕ Open access · CC-BY

Sex differences in pharmacological interventions and their effects on lifespan and healthspan outcomes: a systematic review

▲ 23

GeroScience · 2024

⊕ Open access · CC-BY

Improved resilience and proteostasis mediate longevity upon DAF-2 degradation in old age

▲ 18

Frontiers in Aging · 2024

⊕ Open access · CC-BY

Climbing the longevity pyramid: overview of evidence-driven healthcare prevention strategies for human longevity

▲ 16

International Journal of Molecular Sciences · 2023

⊕ Open access · CC-BY

AI-Predicted mTOR Inhibitor Reduces Cancer Cell Proliferation and Extends the Lifespan of C. elegans

▲ 15

Preprints.org · 2019

⊕ Preprint · CC-BY

The Matrisome during Aging and Longevity: A Systems-Level Approach towards Defining Matreotypes Promoting Healthy Aging

▲ 11

Preprints.org · 2023

⊕ Preprint · CC-BY

AI-Predicted mTOR Inhibitor Reduces Cancer Cell Proliferation and Extends the Lifespan of C. elegans

▲ 4

Preprints.org · 2022

⊕ Preprint · CC-BY

Potential Synergistic Supplementation of NAD+ Promoting Compounds as a Strategy for Increasing Healthspan

▲ 2

FEBS Journal · 2026

⊕ Open access · CC-BY

Combating ageing beyond the cell: Emerging roles of extracellular proteostasis

▲ 1

Aging Cell · 2026

⊕ Open access · CC-BY

An Extracellular Matrix Aging Clock Based on Circulating Matrisome Proteins Predicts Biological Aging and Disease

▲ 1

bioRxiv (Cold Spring Harbor Laboratory) · 2021

⊕ Preprint · CC-BY

Longevity interventions temporally scale healthspan in Caenorhabditis elegans

▲ 1

bioRxiv (Cold Spring Harbor Laboratory) · 2021

⊕ Preprint · CC-BY

Rilmenidine mimics caloric restriction via the nischarin I1-imidazoline receptor to extend lifespan in C. elegans

▲ 0

bioRxiv (Cold Spring Harbor Laboratory) · 2026

⊕ Preprint · CC-BY

Pharmacologic AMPK Activation Extends Lifespan in C. elegans and Improves Aspects of Healthspan in Mice

▲ 0

bioRxiv (Cold Spring Harbor Laboratory) · 2026

⊕ Preprint · CC-BY

Strong inhibition of insulin/IGF-1 signaling in early-mid adulthood compresses morbidity, but in later life accelerates aging

▲ 0