Carlos Cruchaga

Nature reviews. Immunology · 2024

⊕ Preprint · OA

Neuroinflammation in Alzheimer disease

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Science Translational Medicine · 2023

⊕ Preprint · OA

Gut microbiome composition may be an indicator of preclinical Alzheimer’s disease

▲ 353

Molecular Neurodegeneration · 2019

⊕ Open access · CC-BY

Early increase of CSF sTREM2 in Alzheimer’s disease is associated with tau related-neurodegeneration but not with amyloid-β pathology

▲ 347

Nature Medicine · 2025

⊕ Open access · CC-BY

The Global Neurodegeneration Proteomics Consortium: biomarker and drug target discovery for common neurodegenerative diseases and aging

▲ 130

EMBO Molecular Medicine · 2018

⊕ Open access · CC-BY

CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline

▲ 109

BMC Neurology · 2017

⊕ Open access · CC-BY

Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels

▲ 85

PLoS ONE · 2013

⊕ Open access · CC-BY

Characterizing the Role of Brain Derived Neurotrophic Factor Genetic Variation in Alzheimer’s Disease Neurodegeneration

▲ 58

Aging Cell · 2024

⊕ Open access · CC-BY

An interpretable machine learning‐based cerebrospinal fluid proteomics clock for predicting age reveals novel insights into brain aging

▲ 11

Neurobiology of Aging · 2025

⊕ Open access · CC-BY

Proteomic polygenic risk scores of age-related plasma protein levels reveal a role for Metalloproteinase inhibitor 2 (TIMP2) in cognitive performance

▲ 3

medRxiv · 2024

⊕ Preprint · CC-BY

Polygenic proxies of age-related plasma protein levels reveal TIMP2 role in cognitive performance

▲ 2

Figshare · 2017

⊕ Preprint · CC-BY

Additional file 1: of Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels

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Alzheimer s & Dementia · 2024

⊕ Open access · CC-BY

Genetic analyses of the plasma proteome and metabolome from the same cohort pinpoint AD risk associated molecular phenotypes

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Research Square · 2026

⊕ Preprint · CC-BY

Identifying Age-Related Protein Mechanisms of Alzheimer's Disease Amyloidosis from Cerebrospinal Fluid Proteomics Using a Novel Machine Learning Approach

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