Author
Brian Keith Kennedy
- Indexed works
- 48
- Total citations
- 9,891
- Active years
- 20
Collaborators
Works in the record
Cell 2014
Open access · OA
Geroscience: Linking Aging to Chronic Disease
Genes & Development 2006
Preprint · OA
Extension of chronological life span in yeast by decreased TOR pathway signaling
Journal of Biological Chemistry 2005
Open access · CC-BY
Substrate-specific Activation of Sirtuins by Resveratrol
Cell 2023
Open access · OA
Biomarkers of aging for the identification and evaluation of longevity interventions
Aging Cell 2015
Open access · CC-BY
Interventions to Slow Aging in Humans: Are We Ready?
Nature Reviews Drug Discovery 2020
Preprint · OA
The quest to slow ageing through drug discovery
PLoS Biology 2004
Open access · CC-BY
Sir2-Independent Life Span Extension by Calorie Restriction in Yeast
Cell 2025
Open access · OA
From geroscience to precision geromedicine: Understanding and managing aging
Cell Cycle 2009
Open access · OA
A molecular mechanism of chronological aging in yeast
PLoS Genetics 2011
Open access · CC-BY
Elevated Proteasome Capacity Extends Replicative Lifespan in Saccharomyces cerevisiae
PLoS Genetics 2007
Open access · CC-BY
Recent Developments in Yeast Aging
Nature Communications 2019
Open access · CC-BY
A novel rapamycin analog is highly selective for mTORC1 in vivo
PLoS Genetics 2005
Open access · CC-BY
Increased Life Span due to Calorie Restriction in Respiratory-Deficient Yeast
Aging Cell 2015
Open access · CC-BY
Rapamycin‐mediated mTORC 2 inhibition is determined by the relative expression of FK 506‐binding proteins
BMC Developmental Biology 2008
Open access · CC-BY
Age- and calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans
The Journals of Gerontology Series A 2008
Citation only
A Method for High-Throughput Quantitative Analysis of Yeast Chronological Life Span
PLoS Genetics 2013
Open access · CC-BY
A Natural Polymorphism in rDNA Replication Origins Links Origin Activation with Calorie Restriction and Lifespan
Aging Cell 2006
Open access · OA
Sirtuin‐independent effects of nicotinamide on lifespan extension from calorie restriction in yeast
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2018
Open access · OA
The yeast replicative aging model
Cell Cycle 2011
Open access · OA
A genomic analysis of chronological longevity factors in budding yeast
Cell Metabolism 2014
Open access · OA
Inactivation of Yeast Isw2 Chromatin Remodeling Enzyme Mimics Longevity Effect of Calorie Restriction via Induction of Genotoxic Stress Response
The EMBO Journal 2022
Open access · OA
Unfolded protein response IRE1/XBP1 signaling is required for healthy mammalian brain aging
Nature Aging 2024
Open access · CC-BY
Principal component-based clinical aging clocks identify signatures of healthy aging and targets for clinical intervention
FEBS Journal 2021
Open access · OA
Targeting the molecular & cellular pillars of human aging with exercise
Nature 2009
Citation only
A midlife longevity drug?
eLife 2022
Open access · CC-BY
Tom70-based transcriptional regulation of mitochondrial biogenesis and aging
GeroScience 2023
Open access · CC-BY
Alpha-ketoglutarate supplementation and BiologicaL agE in middle-aged adults (ABLE)—intervention study protocol
Journal of Clinical Investigation 2019
Open access · OA
Mixing old and young: enhancing rejuvenation and accelerating aging
Cell Cycle 2013
Open access · OA
Chronic rapamycin treatment or lack ofS6K1does not reduce ribosome activity in vivo
AGE 2015
Open access · OA
PMT1 deficiency enhances basal UPR activity and extends replicative lifespan of Saccharomyces cerevisiae
Ageing Research Reviews 2024
Preprint · OA
The impact of short-lived controls on the interpretation of lifespan experiments and progress in geroscience – Through the lens of the “900-day rule”
Cell Cycle 2012
Open access · OA
Niche science: The aging stem cell
Frontiers in Aging 2022
Open access · CC-BY
LipidClock: A Lipid-Based Predictor of Biological Age
Ageing Research Reviews 2021
Open access · CC-BY
Targeting impaired nutrient sensing with repurposed therapeutics to prevent or treat age-related cognitive decline and dementia: A systematic review
The Journals of Gerontology Series A 2019
Open access · OA
Mechanistic target of rapamycin signaling in mouse models of accelerated aging
Aging 2025
Open access · CC-BY
DoliClock: a lipid-based aging clock reveals accelerated aging in neurological disorders
Aging 2012
Open access · CC-BY
The second international conference "genetics of aging and longevity"
Life Science Alliance 2024
Open access · CC-BY
Late-life dietary folate restriction reduces biosynthesis without compromising healthspan in mice
GeroScience 2025
Preprint · OA
Slowing down the clock on ovarian aging—does the ovary hold the secret to the fountain of youth?
General Psychiatry 2025
Open access · CC-BY
Spermidine for cognitive ageing: insights into observational and interventional studies
Aging and Disease 2026
Open access · CC-BY
A Pathology-Trained Lipid Aging Clock Reveals Accelerated Aging and Prognostic Sphingolipid Signatures in Pancreatic Disease
Springer eBooks 2021
Citation only
Geroscience
Innovation in Aging 2018
Open access · OA
TARGETING AGEING IN ASIA
Metabolism 2026
Citation only
Obesity and biological aging across the life course: A geroscience framework for metabolic health
Research Square 2026
Preprint · CC-BY
Building a clinical platform for response-guided geroscience: safety and feasibility in the randomized ELITE pilot trial
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature 2018
Preprint
Faculty Opinions recommendation of Fisetin is a senotherapeutic that extends health and lifespan.
Springer eBooks 2020
Citation only
Geroscience
Zenodo (CERN European Organization for Nuclear Research) 2015
Preprint · CC-BY