Author
Brian K. Kennedy
- Indexed works
- 52
- Total citations
- 14,097
- Active years
- 20
Collaborators
Works in the record
Cell 2014
Open access · OA
Geroscience: Linking Aging to Chronic Disease
Cancer Discovery 2016
Open access · OA
Cellular Senescence Promotes Adverse Effects of Chemotherapy and Cancer Relapse
Genes & Development 2006
Preprint · OA
Extension of chronological life span in yeast by decreased TOR pathway signaling
Cell Metabolism 2015
Open access · OA
A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan
Journal of Biological Chemistry 2005
Open access · CC-BY
Substrate-specific Activation of Sirtuins by Resveratrol
Cell 2023
Open access · OA
Biomarkers of aging for the identification and evaluation of longevity interventions
Nature 2009
Preprint · OA
Histone H4 lysine 16 acetylation regulates cellular lifespan
Aging Cell 2015
Open access · CC-BY
Interventions to Slow Aging in Humans: Are We Ready?
Nature Reviews Drug Discovery 2020
Preprint · OA
The quest to slow ageing through drug discovery
PLoS Biology 2004
Open access · CC-BY
Sir2-Independent Life Span Extension by Calorie Restriction in Yeast
Cell 2025
Open access · OA
From geroscience to precision geromedicine: Understanding and managing aging
Cell Cycle 2009
Open access · OA
A molecular mechanism of chronological aging in yeast
Nature Medicine 2024
Open access · OA
Validation of biomarkers of aging
PLoS Genetics 2011
Open access · CC-BY
Elevated Proteasome Capacity Extends Replicative Lifespan in Saccharomyces cerevisiae
PLoS Genetics 2007
Open access · CC-BY
Recent Developments in Yeast Aging
Genes & Development 2015
Preprint · CC-BY
H3K36 methylation promotes longevity by enhancing transcriptional fidelity
Nature Communications 2019
Open access · CC-BY
A novel rapamycin analog is highly selective for mTORC1 in vivo
PLoS Genetics 2005
Open access · CC-BY
Increased Life Span due to Calorie Restriction in Respiratory-Deficient Yeast
Aging Cell 2015
Open access · CC-BY
Rapamycin‐mediated mTORC 2 inhibition is determined by the relative expression of FK 506‐binding proteins
BMC Developmental Biology 2008
Open access · CC-BY
Age- and calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans
The Journals of Gerontology Series A 2008
Open access · OA
A Method for High-Throughput Quantitative Analysis of Yeast Chronological Life Span
Cell Metabolism 2020
Open access · OA
A Conserved Mito-Cytosolic Translational Balance Links Two Longevity Pathways
Aging Cell 2016
Open access · CC-BY
Developing criteria for evaluation of geroprotectors as a key stage toward translation to the clinic
Aging 2015
Open access · CC-BY
Geroprotectors.org: a new, structured and curated database of current therapeutic interventions in aging and age-related disease
PLoS Genetics 2013
Open access · CC-BY
A Natural Polymorphism in rDNA Replication Origins Links Origin Activation with Calorie Restriction and Lifespan
Aging Cell 2006
Open access · OA
Sirtuin‐independent effects of nicotinamide on lifespan extension from calorie restriction in yeast
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2018
Open access · OA
The yeast replicative aging model
PLoS Genetics 2014
Open access · CC-BY
Enhanced Longevity by Ibuprofen, Conserved in Multiple Species, Occurs in Yeast through Inhibition of Tryptophan Import
Cell Cycle 2011
Open access · OA
A genomic analysis of chronological longevity factors in budding yeast
Cell Research 2023
Preprint · CC-BY
Unraveling female reproductive senescence to enhance healthy longevity
PLoS Genetics 2014
Open access · CC-BY
Lifespan Extension Conferred by Endoplasmic Reticulum Secretory Pathway Deficiency Requires Induction of the Unfolded Protein Response
The EMBO Journal 2022
Open access · OA
Unfolded protein response IRE1/XBP1 signaling is required for healthy mammalian brain aging
European Journal of Nutrition 2019
Open access · CC-BY
Nutrition interventions for healthy ageing across the lifespan: a conference report
Frontiers in Aging Neuroscience 2024
Open access · CC-BY
Neural ageing and synaptic plasticity: prioritizing brain health in healthy longevity
The Journals of Gerontology Series A 2015
Open access · OA
Preparing for an Aging World: Engaging Biogerontologists, Geriatricians, and the Society
Cell Cycle 2011
Open access · OA
Quantitative evidence for early life fitness defects from 32 longevity-associated alleles in yeast
Aging 2024
Open access · CC-BY
Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity
bioRxiv (Cold Spring Harbor Laboratory) 2019
Preprint · OA
Alpha-ketoglutarate, an endogenous metabolite, extends lifespan and compresses morbidity in aging mice
Cell Reports 2013
Open access · CC-BY
Integration of Multiple Nutrient Cues and Regulation of Lifespan by Ribosomal Transcription Factor Ifh1
Cell Cycle 2012
Open access · CC-BY
Chronological and replicative lifespan in yeast
Cell Cycle 2013
Open access · OA
Chronic rapamycin treatment or lack ofS6K1does not reduce ribosome activity in vivo
Journal of Clinical Investigation 2019
Open access · OA
Mixing old and young: enhancing rejuvenation and accelerating aging
Aging 2023
Open access · CC-BY
Brief, weekly magnetic muscle therapy improves mobility and lean body mass in older adults: a Southeast Asia community case study
AGE 2015
Open access · OA
PMT1 deficiency enhances basal UPR activity and extends replicative lifespan of Saccharomyces cerevisiae
Aging Cell 2007
Citation only
Does resveratrol activate yeast Sir2 in vivo?
JBMR Plus 2021
Open access · CC-BY
Longitudinal Functional Study of Murine Aging: A Resource for Future Study Designs
Current Genomics 2012
Open access · OA
Genome-Scale Studies of Aging: Challenges and Opportunities
Ageing Research Reviews 2021
Open access · CC-BY
Targeting impaired nutrient sensing with repurposed therapeutics to prevent or treat age-related cognitive decline and dementia: A systematic review
Ageing Research Reviews 2024
Preprint · OA
The impact of short-lived controls on the interpretation of lifespan experiments and progress in geroscience – Through the lens of the “900-day rule”
The Journals of Gerontology Series A 2019
Open access · OA